335166-00-2
335166-00-2
Chemical Structure
iMAC2 hydrochloride
- CAS. Nr.: 335166-00-2
- Formula:C19H22Br2Cl2FN3
- Molecular Weight:542.11
IUPAC Name: 3,6-dibromo-9-(2-fluoro-3-(piperazin-1-yl)propyl)-9H-carbazole dihydrochloride
InChIKey: JWCVUOLQOHIRML-UHFFFAOYSA-N
SMILES: FC(CN1CCNCC1)CN2C3=C(C4=C2C=CC(Br)=C4)C=C(Br)C=C3.Cl.Cl
Biological Activity: iMAC2 hydrochloride is a potent MAC (mitochondrial apoptosis-induced channel) inhibitor, with an IC50 of 28 nM and a LD50 of 15000 nM. iMAC2 hydrochloride shows anti-apoptotic effect. iMAC2 hydrochloride blocks cytochrome c release[1].
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iMAC2 hydrochloride | 93.98% | iMAC2 hydrochloride is a potent MAC (mitochondrial apoptosis-induced channel) inhibitor, with an IC50 of 28 nM and a LD50 of 15000 nM. iMAC2 hydrochloride shows anti-apoptotic effect. iMAC2 hydrochloride blocks cytochrome c release. | ||||||||||||||||||||
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References
Keywords
