354543-09-2
354543-09-2
Chemical Structure
LQZ-7F
- CAS No.: 354543-09-2
- Formula:C14H7N9O3
- Molecular Weight:349.26
IUPAC Name: (E)-4-amino-N'-(9H-indeno[1,2-b][1,2,5]oxadiazolo[3,4-e]pyrazin-9-ylidene)-1,2,5-oxadiazole-3-carbohydrazide
InChIKey: KLSWJENGNAPRTN-QGMBQPNBSA-N
SMILES: O=C(C1=NON=C1N)N/N=C2C3=C(C4=NC5=NON=C5N=C4\2)C=CC=C3
Biological Activity: LQZ-7F, a survivin dimerization inhibitor, induces spontaneous apoptosis and synergizes with Docetaxel in prostate cancer cells. LQZ-7F dose-dependently inhibits survival of both PC-3 and C4-2 cells with IC50s of 2.99 and 2.47 µM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
LQZ-7F | 97.44% | LQZ-7F, a survivin dimerization inhibitor, induces spontaneous apoptosis and synergizes with Docetaxel in prostate cancer cells. LQZ-7F dose-dependently inhibits survival of both PC-3 and C4-2 cells with IC50s of 2.99 and 2.47 µM, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.58
HY-10949SMER3 -
Similarity Score 0.50
HY-107600IQ-3 -
Similarity Score 0.50
HY-172614RK-0080552 -
Similarity Score 0.46
HY-100233AIQ-1S -
Similarity Score 0.46
HY-50736DUB-IN-1 -
Similarity Score 0.46
HY-100233RIQ-1S free acid (Standard) -
Similarity Score 0.46
HY-147928Apoptotic agent-2 -
Similarity Score 0.45
HY-50737ADUB-IN-2 -
Similarity Score 0.45
HY-50737DUB-IN-3 -
Explore the MedChemAI to find more analogs
