354543-09-2
354543-09-2
Chemical Structure
LQZ-7F
- CAS No.: 354543-09-2
- Formula:C14H7N9O3
- Molecular Weight:349.26
IUPAC Name: (E)-4-amino-N'-(9H-indeno[1,2-b][1,2,5]oxadiazolo[3,4-e]pyrazin-9-ylidene)-1,2,5-oxadiazole-3-carbohydrazide
InChIKey: KLSWJENGNAPRTN-QGMBQPNBSA-N
SMILES: O=C(C1=NON=C1N)N/N=C2C3=C(C4=NC5=NON=C5N=C4\2)C=CC=C3
Biological Activity: LQZ-7F, a survivin dimerization inhibitor, induces spontaneous apoptosis and synergizes with Docetaxel in prostate cancer cells. LQZ-7F dose-dependently inhibits survival of both PC-3 and C4-2 cells with IC50s of 2.99 and 2.47 µM, respectively[1].
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LQZ-7F | 97.44% | LQZ-7F, a survivin dimerization inhibitor, induces spontaneous apoptosis and synergizes with Docetaxel in prostate cancer cells. LQZ-7F dose-dependently inhibits survival of both PC-3 and C4-2 cells with IC50s of 2.99 and 2.47 µM, respectively. | ||||||||||||||||||||
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References
Keywords
