378775-98-5
378775-98-5
Chemical Structure
AK-IN-1
- CAS No.: 378775-98-5
- Formula:C22H21N3O4
- Molecular Weight:391.42
IUPAC Name: 3,7,7-trimethyl-4-(thiophen-3-yl)-1,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b]quinolin-5-one
InChIKey: ARBUGBBNEFAECO-UHFFFAOYSA-N
SMILES: OCCNC1=NC=NC2=C1C(C3=CC=C(OC)C=C3)=C(C4=CC=C(C=C4)OC)O2
Biological Activity: AK-IN-1 is a competitive inhibitor of adenosine kinase (AK) with respect to adenosine (Ado) and uncompetitive with respect to ATP. AK-IN-1 inhibits cellular adenosine uptake and adenosine incorporation into macromolecules. AK-IN-1 can be used for research on ischemia, inflammation, and epilepsy[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AK-IN-1 | 99.71% | AK-IN-1 is a competitive inhibitor of adenosine kinase (AK) with respect to adenosine (Ado) and uncompetitive with respect to ATP. AK-IN-1 inhibits cellular adenosine uptake and adenosine incorporation into macromolecules. AK-IN-1 can be used for research on ischemia, inflammation, and epilepsy. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.62
HY-15290AIM-100 -
Similarity Score 0.58
HY-125741GW768505A free base -
Similarity Score 0.57
HY-18213EGFR-IN-9 -
Similarity Score 0.55
HY-128778Gozanertinib -
Similarity Score 0.50
HY-1832596,7-Dimethoxy-1,3-bis(4-methoxyphenyl)isoquinoline -
Similarity Score 0.50
HY-144441NSC81111 -
Similarity Score 0.50
HY-112294TIE-2/VEGFR-2 kinase-IN-1 -
Similarity Score 0.49
HY-120561PC-046 -
Similarity Score 0.49
HY-116434LY 189332 -
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