475-25-2
475-25-2
Chemical Structure
Hematein
- CAS No.: 475-25-2
- Formula:C16H12O6
- Molecular Weight:300.26
IUPAC Name: 3,4,6a,10-tetrahydroxy-6a,7-dihydroindeno[2,1-c]chromen-9(6H)-one
InChIKey: HLUCICHZHWJHLL-UHFFFAOYSA-N
SMILES: O=C1C=C2CC3(C(C4=CC=C(C(O)=C4OC3)O)=C2C=C1O)O
Biological Activity: Hematein is a oxidation product of hematoxylin acted as a dye[1]. Hematein is an allosteric casein kinase II inhibitor with an IC50 of 0.74 μM. Hematein inhibits Akt/PKB Ser129 phosphorylation, the Wnt/TCF pathway and increases apoptosis in lung cancer cells[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Hematein | 59.09% | Hematein is a oxidation product of hematoxylin acted as a dye. Hematein is an allosteric casein kinase II inhibitor with an IC50 of 0.74 μM. Hematein inhibits Akt/PKB Ser129 phosphorylation, the Wnt/TCF pathway and increases apoptosis in lung cancer cells. | ||||||||||||||||||||
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