480-39-7
480-39-7
Chemical Structure
Pinocembrin
Synonym(s): (+)-Pinocoembrin; Dihydrochrysin; Galangin flavanone
- CAS No.: 480-39-7
- Formula:C15H12O4
- Molecular Weight:256.25
IUPAC Name: (S)-5,7-dihydroxy-2-phenylchroman-4-one
InChIKey: URFCJEUYXNAHFI-ZDUSSCGKSA-N
SMILES: O=C1C[C@@H](C2=CC=CC=C2)OC3=CC(O)=CC(O)=C13
Biological Activity: Pinocembrin ((+)-Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase, and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pinocembrin | 99.68% | Pinocembrin ((+)-Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase, and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties. | ||||||||||||||||||||
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Pinocembrin (Standard) | 99.72% | Pinocembrin (Standard) is the analytical standard of Pinocembrin. This product is intended for research and analytical applications. Pinocembrin ((+)-Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase, and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties. | ||||||||||||||||||||
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(-)-Pinocembrin | 99.93% | (-)-Pinocembrin exhibits anti-mycobacterium activity against mycobacteriuum tuberculosis H37Ra with an IC50 value of 1.11 mg/mL in dormant phase and 1.21 mg/mL in active phase, respectively. (-)-Pinocembrin has potent antiproliferative activity with IC50 values of 1.88-11.00 mg/mL against THP-1, A549, Panc-1, HeLa and MCF7 cell lines. | ||||||||||||||||||||
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Naringenin | 99.28% | Naringenin is the predominant flavanone in Citrus reticulata Blanco; displays strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity. | ||||||||||||||||||||
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Alpinetin | 99.65% | Alpinetin is a flavonoid isolated from cardamom and possesses antitumor, antiinflammation, hepatoprotective, cardiovascular protective, lung protective, antibacterial, antiviral, neuroprotective properties. Alpinetin inhibits lipopolysaccharide (LPS)-induced inflammation, activates PPAR-γ, activates Nrf2, and inhibits TLR4 expression to protect LPS-induced renal injury. | ||||||||||||||||||||
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(Rac)-Alpinetin (Standard) | (Rac)-Alpinetin (Standard) is the analytical standard of (Rac)-Alpinetin. This product is intended for research and analytical applications. (Rac)-Alpinetin is the racemate of Alpinetin (HY-N0625A). | |||||||||||||||||||||
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Pinostrobin | 99.97% | Pinostrobin is a flavonoid with anti-cancer, antioxidant, antiviral and neuroprotective activities. Pinostrobin has oral activity. Pinostrobin is a potent PCSK9 inhibitor that inhibits the catalytic activity of PCSK9. Pinostrobin can be used in the research of viral infections, cancer, leukemia, cardiovascular and cerebrovascular diseases, cirrhosis, inflammation and neurological diseases. | ||||||||||||||||||||
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(±)-Pinocembrin (Standard) | 99.47% | (±)-Pinocembrin (Standard) is the analytical standard of (±)-Pinocembrin. This product is intended for research and analytical applications. (±)-Pinocembrin ((±)-5,7-Dihydroxyflavanone) is a GPR120 ligand able to promote wound healing in HaCaT cell line. | ||||||||||||||||||||
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Pinocembrin, 7-acetate | Pinocembrin, 7-acetate is a Flavonoids product that can be isolated from the herbs of Pinus armandii. | |||||||||||||||||||||
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Dihydrobaicalein | 99.94% | Dihydrobaicalein is a PLK1 Inhibitor with an IC50 of 6.3 μM. Dihydrobaicalein also inhibits VRK2 and PLK2. Dihydrobaicalein is a natural product that can be isolated from Scutellaria scandens. | ||||||||||||||||||||
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(±)-Naringenin | 99.83% | (±)-Naringenin is an orally available anti-inflammatory agent that can regulate both acute and chronic inflammation responses, while also showing antioxidant, neuroprotective, liver-protective, and anti-cancer effects. (±)-Naringenin promotes vasodilation in endothelial cells by activating BKCa channels in muscle cells. It also exerts protective effects against experimental colitis by inhibiting Toll-like receptor 4/NF-κB signaling, making it useful in studies related to sepsis, fulminant hepatitis, fibrosis, and cancer research. | ||||||||||||||||||||
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7-Hydroxyflavanone | 99.59% | 7-Hydroxyflavanone is an aromatase (CYP19) activity inhibitor found in plants with an IC50 of 65 μM, and it also possesses 20S proteasome inhibitory activity. 7-Hydroxyflavanone significantly inhibits primary humoral immunity to SRBC in mice and weakly suppresses DTH. 7-Hydroxyflavanone 1 attenuates Doxorubicin (HY-15142A)-induced oxidative stress, IL-6 inflammation, mitochondrial dysfunction, caspase 3/7 activation, apoptosis, and necrosis, and upregulates the PGC-1α/pAMPK/Beclin-1 autophagy-related pathway. 7-Hydroxyflavanone is extensively metabolized by various fungi, undergoing multiple structural modifications. 7-Hydroxyflavanone can be used in research related to Doxorubicin-induced cardiomyopathy and immune system diseases. | ||||||||||||||||||||
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