482-44-0
482-44-0
Chemical Structure
Imperatorin
Synonym(s): Ammidin
- CAS No.: 482-44-0
- Formula:C16H14O4
- Molecular Weight:270.28
IUPAC Name: 9-((3-methylbut-2-en-1-yl)oxy)-7H-furo[3,2-g]chromen-7-one
InChIKey: OLOOJGVNMBJLLR-UHFFFAOYSA-N
SMILES: O=C1C=CC2=CC3=C(OC=C3)C(OC/C=C(C)/C)=C2O1
Biological Activity: Imperatorin is an effective of NO synthesis inhibitor (IC50=9.2 μmol), which also is a BChE inhibitor (IC50=31.4 μmol). Imperatorin is a weak agonist of TRPV1 with EC50 of 12.6±3.2 μM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Imperatorin | 98.59% | Imperatorin is an effective of NO synthesis inhibitor (IC50=9.2 μmol), which also is a BChE inhibitor (IC50=31.4 μmol). Imperatorin is a weak agonist of TRPV1 with EC50 of 12.6±3.2 μM. | ||||||||||||||||||||
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Imperatorin (Standard) | 98.77% | Imperatorin (Standard) is the analytical standard of Imperatorin. This product is intended for research and analytical applications. Imperatorin is an effective of NO synthesis inhibitor (IC50=9.2 μmol), which also is a BChE inhibitor (IC50=31.4 μmol). Imperatorin is a weak agonist of TRPV1 with EC50 of 12.6±3.2 μM. | ||||||||||||||||||||
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Imperatorin-d6 | Imperatorin-d6 (Ammidin-d6) is the deuterium labeled Imperatorin. Imperatorin is a BChE inhibitor and HIV-1 replication inhibitor. Imperatorin shows mild activity against Gram-negative bacteria. | |||||||||||||||||||||
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Methoxsalen | 99.97% | Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor. | ||||||||||||||||||||
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(-)-Heraclenol | 99.91% | (-)-Heraclenol is a derivative of furocoumarin isolated from Ducrosia anethifolia. (-)-Heraclenol shows antiproliferative and cytotoxic activities on cancer cell lines. | ||||||||||||||||||||
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Pabularinone | Pabularinone is a compound found in the plant Clausena lansium. Pabularinone has potent cytotoxic activity, and its activity showed inhibitory effects in human breast cancer (MCF-7) cells (IC50: 33.74 μg/mL). Pabularinone can be used in anti-tumor research. | |||||||||||||||||||||
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Lansiumarin A | Lansiumarin A is a natural coumarin. | |||||||||||||||||||||
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(Rac)-Isogosferol | (Rac)-Isogosferol ((Rac)-Isogospherol) is a furanocoumarin present in the fruits of Cnidium monnieri(L.) Cusson. | |||||||||||||||||||||
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Phellopterin | 99.94% | Phellopterin, an orally active furocoumarin with multiple biological activities. Phellopterin is a partial agonist of the central benzodiazepine receptors. Phellopterin exerts anti-inflammatory effects by upregulating SIRT1, downregulating ICAM-1 (reducing chronic inflammation, aiding diabetic ulcer healing), inhibiting STAT3 phosphorylation (easing atopic dermatitis inflammation), regulating Akt/PKC pathways (lowering TNF-α-induced VCAM-1 to block monocyte adhesion), and inhibiting TLR4/NF-κB pathway and macrophage M2 polarization (alleviating colitis-related cancers). Phellopterin suppresses ovarian cancer progression via inhibiting the PU.1/CLEC5A/PI3K-AKT loop (inducing cell cycle arrest, apoptosis, DNA damage). Phellopterin alleviates murine diabetes by promoting adipocyte differentiation and increasing PPARγ. Phellopterin also has anti-HSV-1 activity. Phellopterin can be used for studying anti-inflammation, anti-cancer (e.g., ovarian cancer, colitis cancer), blood glucose lowering, anti-diabetes, and anti-virus. | ||||||||||||||||||||
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8-Geranyloxypsoralen (Standard) | ≥98% | 8-Geranyloxypsoralen (Standard) is the analytical standard of 8-Geranyloxypsoralen. This product is intended for research and analytical applications. 8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC50 of 3.93 μM. | ||||||||||||||||||||
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Lansiumarin C | Lansiumarin C, a lansiumarin, can be isolated from the branches of Clausena lansium (Rutaceae). | |||||||||||||||||||||
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Isogosferol | Isogosferol ((+)-Isogospherol; Isogospherol) is a potent anti-inflammatory agent. Isogosferol decreases LPS (HY-D1056)-stimulated NO and IL-1β expression. Isogosferol decreases the LPS (HY-D1056)-stimulated expression of iNOS, COX-2, NF-κB, and pERK1/2. | |||||||||||||||||||||
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Heraclenol | 99.59% | Heraclenol, a coumarin, is isolated from the fruits of Angelica lucida, and exhibits antibacterial activities. | ||||||||||||||||||||
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