BChE Inhibitor

BChE Inhibitors (44):

Cat. No.	Product Name	Effect	Purity

HY-107569

Garcinol	Inhibitor	98.85%
Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC₅₀s of 0.66 µM and 7.39 µM, respectively.

HY-N0285

Imperatorin	Inhibitor	98.00%
Imperatorin is an effective of NO synthesis inhibitor (IC₅₀=9.2 μmol), which also is a BChE inhibitor (IC₅₀=31.4 μmol).

HY-N0226A

Epiberberine chloride	Inhibitor	99.03%
Epiberberine chloride is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor, with IC₅₀s of 1.07, 6.03 and 8.55 μM, respectively.

HY-N0226

Epiberberine	Inhibitor	98.46%
Epiberberine is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor, with IC₅₀s of 1.07, 6.03 and 8.55 μM, respectively.

HY-N2284

Sophoflavescenol	Inhibitor	98.15%
Sophoflavescenol is a prenylated flavonol, which shows great inhibitory activity with IC₅₀ of 0.013 μM against Phosphodiesterase 5 (PDE5), and also inhibits RLAR, HRAR, AGE, BACE1, AChE and BChE with IC₅₀s of 0.30 µM, 0.17 µM, 17.89 µg/mL, 10.98 µM, 8.37 µM and 8.21 µM, respectively.

HY-127087

Isogarcinol	Inhibitor
Isogarcinol (Cambogin) is a potent AChE and BChE inhibitor, with IC₅₀ values of 1.13 and 8.30 μM, respectively.

HY-152113

AChE/BChE/MAO-B-IN-3	Inhibitor
AChE/BChE/MAO-B-IN-3, an indan-1-one derivative, is a potent MAO-B inhibitor with an IC₅₀ of 0.0359 μM for human MAO-B.

HY-N10917

Xanthohumol I	Inhibitor
Xanthohumol I, a chalkone, is a derivative of Xanthohumol (HY-N1067).

HY-107922

Ethopropazine hydrochloride	Inhibitor	99.66%
Ethopropazine (Isothazine) hydrochloride is a potent, selective BChE inhibitor and a poor AChE inhibitor.

HY-151436

ZLMT-12	Inhibitor
ZLMT-12 (compound 35), tacrine derivatives, is a potent, orally active CDK2/9 inhibitor with IC₅₀ values of 0.002 and 0.011 μM for CDK9 and CDK2, respectively.

HY-146669

BChE-IN-6	Inhibitor
BChE-IN-6 (compound 12) is a potent BChE inhibitor, with a K_i of 0.182 μM.

HY-W130236

Methylene Violet 3RAX	Inhibitor
Methylene Violet 3RAX is a phenazine dye to stain the mitochondria of cells.

HY-16183

Echothiopate iodide	Inhibitor
Echothiopate iodide is a potent hBChE (human butyrylcholinesterase) inhibitor.

HY-107275

Ebeiedinone	Inhibitor
Ebeiedinone, a steroidal alkaloid from Fritillaria species, inhibits the bioactivity of human whole blood cholinesterase (ChE) at the concentration of 0.1 mM, with the inhibitory effects of 69.0%.

HY-N7263

Galanthamine N-Oxide	Inhibitor	99.90%
Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor.

HY-151405

Z164597606	Inhibitor
Z164597606 is a selective BChE inhibitor (IC₅₀: 1.3 and 1.7 μM for eqBChE and hBChE).

HY-N10490

Blestrin D	Inhibitor
Blestrin D is a potent butyrylcholinesterase (BChE) mixed-type inhibitor with an IC₅₀ value of 8.1 μM.

HY-152632

BuChE-IN-7	Inhibitor
BuChE-IN-7 is a highly selective inhibitor of hBuChe and eqBuChE with IC₅₀ values of 40 nM, 80 nM respectively.

HY-144446

BuChE-IN-1	Inhibitor
BuChE-IN-1 (Compound 23) is a potent inhibitor of butyrylcholinesterase (BuChE).

HY-152112

AChE/BChE/MAO-B-IN-2	Inhibitor
AChE/BChE/MAO-B-IN-2 is a potent AChE, BChE, and MAO-B enzymes inhibitor with IC₅₀ values of 48.2 nM, 83.9 nM, and 31.2 nM, respectively.

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