4961-41-5
Chemical Structure
Tetraethylenepentamine pentahydrochloride
- CAS No.: 4961-41-5
- Formula:C8H28Cl5N5
- Molecular Weight:371.61
IUPAC Name: N1-(2-aminoethyl)-N2-(2-((2-aminoethyl)amino)ethyl)ethane-1,2-diamine pentahydrochloride
InChIKey: VGICAQBLDJAGSJ-UHFFFAOYSA-N
SMILES: NCCNCCNCCNCCN.[H]Cl.[H]Cl.[H]Cl.[H]Cl.[H]Cl
Biological Activity: Tetraethylenepentamine pentahydrochloride is an orally active copper chelator and copper mobilizer. Tetraethylenepentamine pentahydrochloride exhibits growth inhibitory and hypolipidemic properties. Tetraethylenepentamine pentahydrochloride significantly increases urinary copper excretion and reduces renal copper accumulation in copper overload models, but does not significantly alter hepatic copper levels. Tetraethylenepentamine pentahydrochloride exerts growth inhibitory effects on Candida albicans and Fluconazole (HY-B0101)-resistant strains, and can be widely used in studies related to Wilson's disease and Candida infections[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tetraethylenepentamine pentahydrochloride | 99.79% | Tetraethylenepentamine pentahydrochloride is an orally active copper chelator and copper mobilizer. Tetraethylenepentamine pentahydrochloride exhibits growth inhibitory and hypolipidemic properties. Tetraethylenepentamine pentahydrochloride significantly increases urinary copper excretion and reduces renal copper accumulation in copper overload models, but does not significantly alter hepatic copper levels. Tetraethylenepentamine pentahydrochloride exerts growth inhibitory effects on Candida albicans and Fluconazole (HY-B0101)-resistant strains, and can be widely used in studies related to Wilson's disease and Candida infections. | ||||||||||||||||||||
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- [1]. Domingo JL, et al. Comparative efficacy of several potential treatments for copper mobilization in copper-overloaded rats. Biol Trace Elem Res. 2000;74(2):127-139. [Content Brief]
- [2]. Yousfi H, et al. Repurposing of ribavirin as an adjunct therapy against invasive Candida strains in an in vitro study[J]. Antimicrobial Agents and Chemotherapy, 2019, 63(10): 10.1128/aac. 00263-19.
