54-21-7
54-21-7
Chemical Structure
Sodium Salicylate
Synonym(s): Salicylic acid sodium salt; 2-Hydroxybenzoic acid sodium salt
- CAS No.: 54-21-7
- Formula:C7H5NaO3
- Molecular Weight:160.10
IUPAC Name: sodium 2-hydroxybenzoate
InChIKey: ABBQHOQBGMUPJH-UHFFFAOYSA-M
SMILES: O=C(O[Na])C1=CC=CC=C1O
Biological Activity: Sodium Salicylate (Salicylic acid sodium salt) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation[1]. Sodium Salicylate is also a S6K inhibitor.Sodium Salicylate is a NF-κB inhibitor that decreases inflammatory gene expression and improves repair in aged muscle[4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Sodium Salicylate | 99.99% | Sodium Salicylate (Salicylic acid sodium salt) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. Sodium Salicylate is also a S6K inhibitor.Sodium Salicylate is a NF-κB inhibitor that decreases inflammatory gene expression and improves repair in aged muscle. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Sodium Salicylate (Standard) | 99.92% | Sodium Salicylate (Standard) is the analytical standard of Sodium Salicylate. This product is intended for research and analytical applications. Sodium Salicylate (Salicylic acid sodium salt) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. Sodium Salicylate is also a S6K inhibitor.Sodium Salicylate is a NF-κB inhibitor that decreases inflammatory gene expression and improves repair in aged muscle. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.88
HY-B1681Lithium salicylate -
Similarity Score 0.88
HY-Y0189Methyl Salicylate -
Similarity Score 0.86
HY-W010164R4-Hydroxybenzoate sodium (Standard) -
Similarity Score 0.86
HY-W0167042,5-Dihydroxybenzoic acid sodium -
Similarity Score 0.84
HY-B0167Salicylic acid -
Similarity Score 0.84
HY-B0167S1Salicylic acid-13C6 -
Similarity Score 0.84
HY-W345051Phthalic acid sodium -
Similarity Score 0.84
HY-Y1316Sodium benzoate -
Similarity Score 0.84
HY-Y1074Ethyl salicylate -
Explore the MedChemAI to find more analogs
References
- [1]. Mitchell JA, et al. Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid. Mol Pharmacol. 1997 Jun;51(6):907-12. [Content Brief]
- [4]. Juhyun Oh, et al. Age-associated NF-κB signaling in myofibers alters the satellite cell niche and re-strains muscle stem cell function. Aging (Albany NY). 2016 Nov; 8(11): 2871–2884. [Content Brief]
