54-21-7
54-21-7
Chemical Structure
Sodium Salicylate
Synonym(s): Salicylic acid sodium salt; 2-Hydroxybenzoic acid sodium salt
- CAS No.: 54-21-7
- Formula:C7H5NaO3
- Molecular Weight:160.10
IUPAC Name: sodium 2-hydroxybenzoate
InChIKey: ABBQHOQBGMUPJH-UHFFFAOYSA-M
SMILES: O=C(O[Na])C1=CC=CC=C1O
Biological Activity: Sodium Salicylate (Salicylic acid sodium salt) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation[1]. Sodium Salicylate is also a S6K inhibitor.Sodium Salicylate is a NF-κB inhibitor that decreases inflammatory gene expression and improves repair in aged muscle[4].
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Sodium Salicylate | 99.99% | Sodium Salicylate (Salicylic acid sodium salt) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. Sodium Salicylate is also a S6K inhibitor.Sodium Salicylate is a NF-κB inhibitor that decreases inflammatory gene expression and improves repair in aged muscle. | ||||||||||||||||||||
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Sodium Salicylate (Standard) | ≥98% | Sodium Salicylate (Standard) is the analytical standard of Sodium Salicylate. This product is intended for research and analytical applications. Sodium Salicylate (Salicylic acid sodium salt) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. Sodium Salicylate is also a S6K inhibitor.Sodium Salicylate is a NF-κB inhibitor that decreases inflammatory gene expression and improves repair in aged muscle. | ||||||||||||||||||||
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References
- [1]. Mitchell JA, et al. Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid. Mol Pharmacol. 1997 Jun;51(6):907-12. [Content Brief]
- [4]. Juhyun Oh, et al. Age-associated NF-κB signaling in myofibers alters the satellite cell niche and re-strains muscle stem cell function. Aging (Albany NY). 2016 Nov; 8(11): 2871–2884. [Content Brief]
