548-93-6
548-93-6
Chemical Structure
3-Hydroxyanthranilic acid
- CAS No.: 548-93-6
- Formula:C7H7NO3
- Molecular Weight:153.14
IUPAC Name: 2-amino-3-hydroxybenzoic acid
InChIKey: WJXSWCUQABXPFS-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=CC(O)=C1N
Biological Activity: 3-Hydroxyanthranilic acid is a tryptophan metabolite in the kynurenine pathway.3-hydroxyanthranilic acid has anti-inflammatory, neuroprotective, and lipid-lowering effects. 3-hydroxyanthranilic acid can be used for researches of cardiovascular diseases, tumors, and metabolic diseases[1][2][3][4][5][6][7][8].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3-Hydroxyanthranilic acid | 99.79% | 3-Hydroxyanthranilic acid is a tryptophan metabolite in the kynurenine pathway.3-hydroxyanthranilic acid has anti-inflammatory, neuroprotective, and lipid-lowering effects. 3-hydroxyanthranilic acid can be used for researches of cardiovascular diseases, tumors, and metabolic diseases. | ||||||||||||||||||||
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3-Hydroxyanthranilic acid (Standard) | 99.47% | 3-Hydroxyanthranilic acid (Standard) is the analytical standard of 3-Hydroxyanthranilic acid. This product is intended for research and analytical applications. 3-Hydroxyanthranilic acid is a tryptophan metabolite in the kynurenine pathway. | ||||||||||||||||||||
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3-Hydroxyanthranilic acid-d3 | 99.28% | 3-Hydroxyanthranilic acid-d3 is deuterium-labeled 3-Hydroxyanthranilic acid (HY-W001171). | ||||||||||||||||||||
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References
- [1]. Lee WS, et al. The tryptophan metabolite 3-hydroxyanthranilic acid suppresses T cell responses by inhibiting dendritic cell activation. Int Immunopharmacol. 2013 Nov;17(3):721-6. [Content Brief]
- [2]. Lee SM, et al. Tryptophan metabolite 3-hydroxyanthranilic acid selectively induces activated T cell death via intracellular GSH depletion. Immunol Lett. 2010 Aug 16;132(1-2):53-60. [Content Brief]
- [3]. Lee WS, et al. The tryptophan metabolite 3-hydroxyanthranilic acid suppresses T cell responses by inhibiting dendritic cell activation. Int Immunopharmacol. 2013 Nov;17(3):721-6. [Content Brief]
- [4]. Krause D, et al. The tryptophan metabolite 3-hydroxyanthranilic acid plays anti-inflammatory and neuroprotective roles during inflammation: role of hemeoxygenase-1. Am J Pathol. 2011 Sep;179(3):1360-72. [Content Brief]
- [5]. Zhang L, et al. The tryptophan metabolite 3-hydroxyanthranilic acid lowers plasma lipids and decreases atherosclerosis in hypercholesterolaemic mice. Eur Heart J. 2012 Aug;33(16):2025-34. [Content Brief]
- [6]. Pae HO, et al. 3-Hydroxyanthranilic acid, one of L-tryptophan metabolites, inhibits monocyte chemoattractant protein-1 secretion and vascular cell adhesion molecule-1 expression via heme oxygenase-1 induction in human umbilical vein endothelial cells. Atherosclerosis. 2006 Aug;187(2):274-84. [Content Brief]
- [7]. Wang Q, et al. Tryptophan-Derived 3-Hydroxyanthranilic Acid Contributes to Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice In Vivo. Circulation. 2017 Dec 5;136(23):2271-2283. [Content Brief]
- [8]. Zhu F, et al. The combination of Butyricicoccus pullicaecorum and 3-hydroxyanthranilic acid prevents postmenopausal osteoporosis by modulating gut microbiota and Th17/Treg. Eur J Nutr. 2024 Aug;63(5):1945-1959. [Content Brief]
