548-93-6
548-93-6
Chemical Structure
3-Hydroxyanthranilic acid
- CAS No.: 548-93-6
- Formula:C7H7NO3
- Molecular Weight:153.14
IUPAC Name: 2-amino-3-hydroxybenzoic acid
InChIKey: WJXSWCUQABXPFS-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=CC(O)=C1N
Biological Activity: 3-Hydroxyanthranilic acid is a tryptophan metabolite in the kynurenine pathway.3-hydroxyanthranilic acid has anti-inflammatory, neuroprotective, and lipid-lowering effects. 3-hydroxyanthranilic acid can be used for researches of cardiovascular diseases, tumors, and metabolic diseases[1][2][3][4][5][6][7][8].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3-Hydroxyanthranilic acid | 99.79% | 3-Hydroxyanthranilic acid is a tryptophan metabolite in the kynurenine pathway.3-hydroxyanthranilic acid has anti-inflammatory, neuroprotective, and lipid-lowering effects. 3-hydroxyanthranilic acid can be used for researches of cardiovascular diseases, tumors, and metabolic diseases. | ||||||||||||||||||||
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3-Hydroxyanthranilic acid (Standard) | 99.47% | 3-Hydroxyanthranilic acid (Standard) is the analytical standard of 3-Hydroxyanthranilic acid. This product is intended for research and analytical applications. 3-Hydroxyanthranilic acid is a tryptophan metabolite in the kynurenine pathway. | ||||||||||||||||||||
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3-Hydroxyanthranilic acid-d3 | 99.28% | 3-Hydroxyanthranilic acid-d3 is deuterium-labeled 3-Hydroxyanthranilic acid (HY-W001171). | ||||||||||||||||||||
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5-Aminosalicylic acid-13C6 hydrochloride | 99.53% | 5-Aminosalicylic acid-13C6 hydrochloride?(Mesalamine-13C6 hydrochloride; 5-ASA-13C6 hydrochloride; Mesalazine-13C6 hydrochloride) is the 13C labeled 5-Aminosalicylic Acidhydrochloride. 5-Aminosalicylic acid-13C6 hydrochloride?acts as a PPARγ agonist, and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. | ||||||||||||||||||||
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5-Aminosalicylic Acid | 99.97% | 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. 5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN). | ||||||||||||||||||||
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5-Aminosalicylic Acid-d3 hydrochloride | 99.00% | 5-Aminosalicylic Acid-d3 (hydrochloride) is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) hydrochloride acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. | ||||||||||||||||||||
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5-Aminosalicylic acid-d3 | 99.38% | 5-Aminosalicylic acid-d3 is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. | ||||||||||||||||||||
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5-Aminosalicylic acid-13C6 | 5-Aminosalicylic acid-13C6 is the 13C labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. | |||||||||||||||||||||
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4-Aminobenzoic acid-d4 | 99.43% | 4-Aminobenzoic acid-d4 is the deuterium labeled 4-Aminobenzoic acid. 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi. | ||||||||||||||||||||
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4-Aminosalicylic acid (Standard) | ≥98% | 4-Aminosalicylic acid (Standard) is the analytical standard of 4-Aminosalicylic acid. This product is intended for research and analytical applications. 4-Aminosalicylic acid is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid is orally active. | ||||||||||||||||||||
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3-Aminobenzoic acid-d4 | 3-Aminobenzoic acid-d4 is the deuterium labeled 3-Aminobenzoic acid. | |||||||||||||||||||||
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Gallic acid-d2 | 99.59% | Gallic acid-d2 is the deuterium labeled Gallic acid. Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2). Gallic acid has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities. | ||||||||||||||||||||
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5-Hydroxyanthranilic acid | 99.85% | 5-Hydroxyanthranilic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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4-Amino-3-hydroxybenzoic acid | 99.77% | 4-Amino-3-hydroxybenzoic acid is an aromatic substrate degradable by Bordetella sp. strain 10d. 4-Amino-3-hydroxybenzoic acid can serve as a carbon source, nitrogen source and energy source for the growth of Bordetella sp. strain 10d. 4-Amino-3-hydroxybenzoic acid acts as a substrate for 2-amino-5-carboxymuconate-6-semialdehyde deaminase and 4-amino-3-hydroxybenzoate 2,3-dioxygenase. | ||||||||||||||||||||
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2-Amino-3-chlorobenzoic acid | 99.94% | 2-Amino-3-chlorobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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3-Amino-4-hydroxybenzoic acid | 99.86% | 3-Amino-4-hydroxybenzoic acid is an endogenous metabolite. | ||||||||||||||||||||
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2-Carboxyphenol-d4 | 99.83% | 2-Carboxyphenol-d4 is the deuterium labeled 2-Carboxyphenol. 2-Carboxyphenol is a plant hormone and mediates host responses against microbial pathogens. | ||||||||||||||||||||
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3-Aminosalicylic acid | 99.06% | 3-Aminosalicylic acid (3-ASA) is a hydroxybenzoic acid compound. 3-Aminosalicylic acid serves as a building block for organic synthesis. It also acts as a potential impurity of 5-Aminosalicylic Acid (HY-15027). | ||||||||||||||||||||
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4-Hydroxybenzhydrazide-d4 | 4-Hydroxybenzhydrazide-d4 is the deuterium labeled 4-Hydroxybenzohydrazide (HY-W012579). | |||||||||||||||||||||
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Pyrocatechuic acid | 99.69% | Pyrocatechuic acid is a normal human benzoic acid metabolite found in plasma, and has increased levels after aspirin ingestion. | ||||||||||||||||||||
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4-Hydroxybenzoic acid-d4 | 99.97% | 4-Hydroxybenzoic acid-d4 is the deuterium labeled 4-Hydroxybenzoic acid. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL. | ||||||||||||||||||||
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2,6-Dihydroxybenzoic acid-d3 | 2,6-Dihydroxybenzoic acid-d3 is the deuterated-labeled 2,6-Dihydroxybenzoic acid (HY-Y0801). 2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater. | |||||||||||||||||||||
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Methyl 3,4-dihydroxybenzoate-d3-1 | Methyl 3,4-dihydroxybenzoate-d3-1 is the deuterium labeled Methyl 3,4-dihydroxybenzoate. Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect. | |||||||||||||||||||||
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References
- [1]. Lee WS, et al. The tryptophan metabolite 3-hydroxyanthranilic acid suppresses T cell responses by inhibiting dendritic cell activation. Int Immunopharmacol. 2013 Nov;17(3):721-6. [Content Brief]
- [2]. Lee SM, et al. Tryptophan metabolite 3-hydroxyanthranilic acid selectively induces activated T cell death via intracellular GSH depletion. Immunol Lett. 2010 Aug 16;132(1-2):53-60. [Content Brief]
- [3]. Lee WS, et al. The tryptophan metabolite 3-hydroxyanthranilic acid suppresses T cell responses by inhibiting dendritic cell activation. Int Immunopharmacol. 2013 Nov;17(3):721-6. [Content Brief]
- [4]. Krause D, et al. The tryptophan metabolite 3-hydroxyanthranilic acid plays anti-inflammatory and neuroprotective roles during inflammation: role of hemeoxygenase-1. Am J Pathol. 2011 Sep;179(3):1360-72. [Content Brief]
- [5]. Zhang L, et al. The tryptophan metabolite 3-hydroxyanthranilic acid lowers plasma lipids and decreases atherosclerosis in hypercholesterolaemic mice. Eur Heart J. 2012 Aug;33(16):2025-34. [Content Brief]
- [6]. Pae HO, et al. 3-Hydroxyanthranilic acid, one of L-tryptophan metabolites, inhibits monocyte chemoattractant protein-1 secretion and vascular cell adhesion molecule-1 expression via heme oxygenase-1 induction in human umbilical vein endothelial cells. Atherosclerosis. 2006 Aug;187(2):274-84. [Content Brief]
- [7]. Wang Q, et al. Tryptophan-Derived 3-Hydroxyanthranilic Acid Contributes to Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice In Vivo. Circulation. 2017 Dec 5;136(23):2271-2283. [Content Brief]
- [8]. Zhu F, et al. The combination of Butyricicoccus pullicaecorum and 3-hydroxyanthranilic acid prevents postmenopausal osteoporosis by modulating gut microbiota and Th17/Treg. Eur J Nutr. 2024 Aug;63(5):1945-1959. [Content Brief]
