581-31-7
581-31-7
Chemical Structure
Suberosin
- CAS No.: 581-31-7
- Formula:C15H16O3
- Molecular Weight:244.29
IUPAC Name: 7-methoxy-6-(3-methylbut-2-en-1-yl)-2H-chromen-2-one
InChIKey: RSZDAYHEZSRVHS-UHFFFAOYSA-N
SMILES: O=C1C=CC2=CC(C/C=C(C)\C)=C(OC)C=C2O1
Biological Activity: Suberosin, isolated from Plumbago zeylanica, exhibits anti-inflammatory and anticoagulant activity. Suberosin suppresses PHA-induced PBMC proliferation and arrested cell cycle progression from the G1 transition to the S phase through the modulation of the transcription factors NF-AT and NF-κB[1][2].
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Suberosin | 99.84% | Suberosin, isolated from Plumbago zeylanica, exhibits anti-inflammatory and anticoagulant activity. Suberosin suppresses PHA-induced PBMC proliferation and arrested cell cycle progression from the G1 transition to the S phase through the modulation of the transcription factors NF-AT and NF-κB. | ||||||||||||||||||||
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References
- [1]. Y-C Chen, et al. Suberosin inhibits proliferation of human peripheral blood mononuclear cells through the modulation of the transcription factors NF-AT and NF-jB. British Journal of Pharmacology (2007) 150, 298-312.
- [2]. Golfakhrabadi F, et al. Anticoagulant activity of isolated coumarins (suberosin and suberenol) and toxicity evaluation of Ferulago carduchorum in rats. Pharm Biol. 2014 Oct;52(10):1335-40. [Content Brief]
Keywords
