6019-39-2
6019-39-2
Chemical Structure
OAC2
- CAS No.: 6019-39-2
- Formula:C15H12N2O
- Molecular Weight:236.27
IUPAC Name: N-(1H-indol-5-yl)benzamide
InChIKey: JCAFGYWSIWYMOX-UHFFFAOYSA-N
SMILES: O=C(NC1=CC2=C(NC=C2)C=C1)C3=CC=CC=C3
Biological Activity: OAC2 is an Oct4-activating compound which activates expression through the Oct4 gene promoter.
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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OAC2 | 98.42% | OAC2 is an Oct4-activating compound which activates expression through the Oct4 gene promoter. | ||||||||||||||||||||
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Naphthol AS-E | 98.0% | Naphthol AS-E is a potent and cell-permeable inhibitor of KIX-KID interaction. Naphthol AS-E directly binds to the KIX domain of CBP (Kd:8.6 μM), blocks the interaction between the KIX domain and the KID domain of CREB with IC50 of 2.26 μM. Naphthol AS-E can be used for cancer research. | ||||||||||||||||||||
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Oct4 inducer-1 | 99.92% | Oct4 inducer-1 (compound OAC-3) is a potent Oct4 activator. Oct4 inducer-1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. Oct4 inducer-1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time. | ||||||||||||||||||||
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OAC1 | 99.85% | OAC1 is a potent Oct4 activator. OAC1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. OAC1 activates OCT4 through upregulation of HOXB4 expression. OAC1 increases transcription of the Oct4-Nanog-Sox2 triad and TET1. OAC1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time. | ||||||||||||||||||||
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PSB-1410 | 99.22% | PSB-1410 is a monoamine oxidase B (MAO-B) inhibitor, with an IC50 of 0.227 nM against human MAO-B and an IC50 of 1.01 nM against rat MAO-B. PSB-1410 can be used for the research of Parkinson's disease. | ||||||||||||||||||||
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2-Aminobenzanilide | 2-Aminobenzamide is a neutral and stable compound used as fluorescent tag, numerously in Glycan analysis. 2-aminobenzamide acts as the starting material for several important reactions like Bargellini reaction as an competent ambident nucleophile. Specifically 2-aminobenzamide and its derivatives are used in the blood coagulation cascade. | |||||||||||||||||||||
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LSD1-IN-12 | LSD1-IN-12 (compound 2) is a potent LSD1 inhibitor, with Ki values of 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), and 3.5 μM (MAO-B), respectively. | |||||||||||||||||||||
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MAO-B-IN-39 | MAO-B-IN-39 (compound11) is a selective monoamine oxidase B (MAO-B) inhibitor. MAO-B-IN-39 inhibits MAO-Bwith an IC50 of 3.61 μM. MAO-B-IN-39 demonstrates a potent NRF2 induction capacity. MAO-B-IN-39 exhibits potent anti-inflammatory and neuroprotective activity in OS (oxidative stress)-related in vitro models. MAO-B-IN-39 demonstrates high liver microsomal stability and favorable pharmacokinetics in mice. MAO-B-IN-39 is potential for Parkinson’s disease (PD) research. | |||||||||||||||||||||
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Tau-aggregation-IN-5 | Tau-aggregation-IN-5 is a Tau-aggregation inhibitor (EC50 = 0.31 μM). Tau-aggregation-IN-5 targets P4HB covalently and activates mild ER stress. Tau-aggregation-IN-4 can be used for the study of neurodegenerative disorders such as Alzheimer’s and Pick’s diseases. | |||||||||||||||||||||
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N4-Benzoylcytosine | 99.21% | N4-Benzoylcytosine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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Dinaline | Dinaline (GOE 1734; PD 104 208; NSC 328786) is a potent and orally activity anticancer agent. Dinaline shows cytotoxicity and antitumor activity. Dinaline has the potential for the research of colorectal cancer. | |||||||||||||||||||||
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