67-45-8

Furazolidone Chemical Structure
67-45-8

Chemical Structure

Furazolidone

  • CAS No.: 67-45-8
  • Formula:C8H7N3O5
  • Molecular Weight:225.16

IUPAC Name: (E)-3-(((5-nitrofuran-2-yl)methylene)amino)oxazolidin-2-one

InChIKey: PLHJDBGFXBMTGZ-WEVVVXLNSA-N

SMILES: O=C1OCCN1/N=C/C2=CC=C([N+]([O-])=O)O2

Biological Activity: Furazolidone is a monoamine oxidase (MAO) inhibitor with antiproliferative, apoptosis-inducing and differentiation-promoting activities. Furazolidone may inhibit leukemia fusion protein-mediated bone marrow transformation by upregulating the stability of the tumor suppressor protein p53. Furazolidone exhibits anti-leukemic activity in acute myeloid leukemia (AML) cell lines and can be used for anti-AML research[1][2].

Cat. No. Product Name Purity Description Pricing
HY-B1336
Furazolidone 99.92% Furazolidone is a monoamine oxidase (MAO) inhibitor with antiproliferative, apoptosis-inducing and differentiation-promoting activities. Furazolidone may inhibit leukemia fusion protein-mediated bone marrow transformation by upregulating the stability of the tumor suppressor protein p53. Furazolidone exhibits anti-leukemic activity in acute myeloid leukemia (AML) cell lines and can be used for anti-AML research.
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HY-B1336R
Furazolidone (Standard) 99.95% Furazolidone (Standard) is the analytical standard of Furazolidone. This product is intended for research and analytical applications. Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity. It inhibits AML1-ETO transformed cells with an IC50 of 12.7 μM.
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HY-B1336S
Furazolidone-d4 Furazolidone-d4 is deuterium labeled Furazolidone.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References