1. Anti-infection
  2. Bacterial
  3. Furazolidone

Furazolidone 

Cat. No.: HY-B1336 Purity: 96.66%
Handling Instructions

Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM.

For research use only. We do not sell to patients.

Furazolidone Chemical Structure

Furazolidone Chemical Structure

CAS No. : 67-45-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
1 g USD 60 In-stock
Estimated Time of Arrival: December 31
5 g   Get quote  
10 g   Get quote  

* Please select Quantity before adding items.

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Based on 1 publication(s) in Google Scholar

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Description

Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM. Target: Antibacterial Furazolidone is a novel therapeutic strategy in AML patients. Furazolidone can Inhibit the bone-marrow transformation mediated by a series of leukemia fusion proteins. Furazolidone significantly inhibits proliferation of AML cell lines. Furazolidone induces apoptosis of the AML leukemic cells treatment with Furazolidone induces differentiation of AML cell lines.

Clinical Trial
Molecular Weight

225.16

Formula

C₈H₇N₃O₅

CAS No.

67-45-8

SMILES

O=C1OCCN1/N=C/C2=CC=C([N+]([O-])=O)O2

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (44.41 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4413 mL 22.2064 mL 44.4129 mL
5 mM 0.8883 mL 4.4413 mL 8.8826 mL
10 mM 0.4441 mL 2.2206 mL 4.4413 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 1 mg/mL (4.44 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 1 mg/mL (4.44 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Furazolidone
Cat. No.:
HY-B1336
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