2. Anti-infection
  3. Antibiotic Bacterial
  4. Nitrofurantoin sodium

Nitrofurantoin sodium is a potent and orally active antibacterial agent. Nitrofurantoin sodium acts as an antibiotic. Nitrofurantoin sodium can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections.

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Nitrofurantoin sodium Chemical Structure

Nitrofurantoin sodium Chemical Structure

CAS No. : 54-87-5

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Nitrofurantoin sodium Related Antibodies

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Description

Nitrofurantoin sodium is a potent and orally active antibacterial agent. Nitrofurantoin sodium acts as an antibiotic. Nitrofurantoin sodium can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections[1][2].

In Vitro

Nitrofurantoin sodium (0-512 mg/L; 8 h) treatment inhibits the growth of E. coli isolates[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Nitrofurantoin sodium Related Antibodies

Cell Viability Assay[3]

Cell Line: E. coli isolates: DA10708, DA13815, DA13824, DA13957, DA13992, DA10626, DA10627
Concentration: 0, 32, 64, 128, 256, and 512 mg/L
Incubation Time: 8 hours
Result: Observed bactericidal effect at 32 mg/L For DA10708, DA13815 and DA13824.
Inhibited the growth of DA13957 and DA13992 completely at 128 mg/L, observed bactericidal effect at 256 mg/L.
Showed a moderate killing at >128 mg/L for DA10626 and DA10627.
In Vivo

1.19 Nitrofurantoin pharmacokinetic effects in SD Rats[4].

Parameters 10 mg/kg p.o. 2 mg/kg i.v.
AUC0-720 (μg/mL•min) 306
AUC0-120 (μg/mL•min) 90.3
AUC0-∞ (μg/mL•min) 344 91.5
Cmax (μg/mL) 1.01
CL/F or CL (ml/min/kg) 31.0 22.7
t1/2 (min) 166 23.6
Bioavailability (%) 60.1

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

261.15

Formula

C8H6N4NaO5
CAS No.
SMILES

O=C1NC(CN1/N=C/C2=CC=C([N+]([O-])=O)O2)=O.[Na]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Nitrofurantoin sodium Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nitrofurantoin54-87-5AntibioticBacterialantimicrobialantibioticurinary tractinfectionUTIcystitiskidneyantibacterialE. coliInhibitorinhibitorinhibit

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