68-19-9
68-19-9
Chemical Structure
Vitamin B12
Synonym(s): Cyanocobalamin
- No. CAS: 68-19-9
- Formula:C63H88CoN14O14P
- Molecular Weight:1355.37
InChIKey: FDJOLVPMNUYSCM-WZHZPDAFSA-L
SMILES: N#[C-][Co+3]([N-]1[C@@]([C@@H]2CC(N)=O)([H])[C@]3([C@](C)4CC(N)=O)C)([N](C([C@](C)5CC(N)=O)=C6C)=C7[C@H]5CCC(N)=O)([N](C(C(C)8C)=C7)=C([C@H]8CCC(N)=O)C(C)=C1[C@@]2(CCC(NC[C@H]9C)=O)C)([N](C%10=C%11)=CN([C@@H](O[C@@H]%12CO)[C@]([C@@H]%12O[P]([O-])(O9)=O)([H])O)C%10=CC(C)=C%11C)[N]3=C6[C@H]4CCC(N)=O
Biological Activity: Vitamin B12 is a vitamin that can pass through the blood-brain barrier. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Vitamin B12 is beneficial for many inflammatory diseases and also provides protection in oxidative-stress-associated pathologies[1][2].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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Vitamin B12 | 99.99% | Vitamin B12 is a vitamin that can pass through the blood-brain barrier. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Vitamin B12 is beneficial for many inflammatory diseases and also provides protection in oxidative-stress-associated pathologies. | ||||||||||||||||||||
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Vitamin B12 (Standard) | 99.95% | Vitamin B12 (Standard) is the analytical standard of Vitamin B12. This product is intended for research and analytical applications. Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood. | ||||||||||||||||||||
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Vitamin B12-13C7 | Vitamin B12-13C7 is the 13C-labeled Vitamin B12. Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood. | |||||||||||||||||||||
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Adenosylcobalamin (Standard) | 98.32% | Adenosylcobalamin (Standard) is the analytical standard of Adenosylcobalamin. This product is intended for research and analytical applications. Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B12 which is a cofactor for methylmalonyl CoA mutase | ||||||||||||||||||||
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Dicyanocobinamide | 94% | Dicyanocobinamide is a precursor to vitamin B12. Dicyanocobinamide is a catalyst for the oxidation of peptides, which is utilized for a rapid, environmentally friendly method of disulfide bond formation in water. Dicyanocobinamide exhibits good biocompatibility. | ||||||||||||||||||||
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2,4-Difluorophenylethynylcobalamin | 98.97% | 2,4-Difluorophenylethynylcobalamin is a potential B12 antivitamin via binding to human B12 -processing enzyme CblC with high affinity (KD=130 nm). 2,4-Difluorophenylethynylcobalamin withstood tailoring by CblC, and stabilizes the ternary complex with the cosubstrate glutathione (GSH). 2,4-Difluorophenylethynylcobalamin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Methylcobalamin-d3 | Methylcobalamin-d3 (Mecobalamin-d3) is the deuterium labeled Methylcobalamin (HY-B0586). Methylcobalamin (CH3-B12), a cobalamin, is a form of vitamin B12. | |||||||||||||||||||||
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Methylcobalamin (Standard) | 96.84% | Methylcobalamin (Standard) is the analytical standard of Methylcobalamin. This product is intended for research and analytical applications. Methylcobalamin (CH3-B12), a cobalamin, is a form of vitamin B12. | ||||||||||||||||||||
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Hydroxocobalamin | 99.32% | Hydroxocobalamin (Vitamin B12a) is a cyanide antidote. Hydroxocobalamin can decrease the cell and plasma cyanide concentrations and increase survival rate in acute cyanide poisoning. Hydroxocobalamin can improve newborn Cbl-C defect-induced metabolic profile and neurocognitive outcome. Hydroxocobalamin can normalize Vitamin B12 deficiency. Hydroxocobalamin can induce acute kidney injury. Hydroxocobalamin can be used for the researches of metabolic and neurological disease. | ||||||||||||||||||||
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Hydroxocobalamin monohydrochloride | 99.57% | Hydroxocobalamin monohydrochloride (Vitamin B12a monohydrochloride) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia. | ||||||||||||||||||||
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Hydroxocobalamin acetate | 98.90% | Hydroxocobalamin acetate is an injectable natural vitamin B12. Hydroxocobalamin acetate binds to NO. Hydroxocobalamin acetate detoxifies Cyanide and NaSH. Hydroxocobalamin acetate reduces hypotension. Hydroxocobalamin acetate is used in research related to vitamin B12 deficiency, including pernicious anemia. | ||||||||||||||||||||
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Methylcobalamin hydrate | Methylcobalamin Hydrate is a coenzyme required for methionine biosynthesis. Vitamins (hematopoiesis). It acts as a histamine receptor, Alzheimer study. Methylcobalamin is also used in the research of peripheral neuropathy, diabetic neuropathy, and as an initial research for amyotrophic lateral sclerosis. It can be used to prevent or research pathologies caused by vitamin B12 deficiency, such as pernicious anemia. | |||||||||||||||||||||
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Cyanocobalamin-e-methylamide | Cyanocobalamin-e-methylamide is a Vitamin B12 (HY-B0315) analogue. Cyanocobalamin-e-methylamide exerts a plasma blocking effect on 57Co-cyanocobalamin. Cyanocobalamin-e-methylamide can be used for the research of chronic myelocytic leukaemia. | |||||||||||||||||||||
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References
- [1]. Banerjee, R. et al. The many faces of vitamin B12: catalysis by cobalamin-dependent enzymes. Annu Rev Biochem, 2003. 72: p. 209-47. [Content Brief]
- [2]. Lai SC, et al. The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system. FASEB J. 2013 Jun;27(6):2468-75. [Content Brief]
