80225-53-2
80225-53-2
Chemical Structure
Rosmanol
- CAS No.: 80225-53-2
- Formula:C20H26O5
- Molecular Weight:346.42
IUPAC Name: (4bR,8aS,9S,10S)-3,4,10-trihydroxy-2-isopropyl-8,8-dimethyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epoxymethano)phenanthren-12-one
InChIKey: LCAZOMIGFDQMNC-FORWCCJISA-N
SMILES: O=C1O[C@]2([H])[C@@H](O)C3=C(C(O)=C(O)C(C(C)C)=C3)[C@@]41CCCC(C)(C)[C@]24[H]
Biological Activity: Rosmanol could inhibit the oxidation of low density lipoprotein (LPL) and significantly inhibit lipopolysaccharide induced iNOS and COX-2 expression, with anti-inflammatory effect.
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Rosmanol | 98.95% | Rosmanol could inhibit the oxidation of low density lipoprotein (LPL) and significantly inhibit lipopolysaccharide induced iNOS and COX-2 expression, with anti-inflammatory effect. | ||||||||||||||||||||
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Rosmanol (Standard) | ≥98% | Rosmanol (Standard) is the analytical standard of Rosmanol. This product is intended for research and analytical applications. Rosmanol could inhibit the oxidation of low density lipoprotein (LPL) and significantly inhibit lipopolysaccharide induced iNOS and COX-2 expression, with anti-inflammatory effect. | ||||||||||||||||||||
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7-Methoxyrosmanol | 99.28% | 7-Methoxyrosmanol (7-O-Methoxyrosmanol), a phenolic diterpene isolated from rosemary, suppresses the cAMP responsiveness of PEPCK and G6Pase promoters. | ||||||||||||||||||||
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Epirosmanol | 99.38% | Epirosmanol is a nature diterpene lactone from S. officinalis. Epirosmanol shows anti-cancer activity and inhibits melanin biosynthesis against melanoma cells. Epirosmanol also exhibits DPPH radical scavenging activity. | ||||||||||||||||||||
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7-Ethoxyrosmanol | 98.47% | 7-Ethoxyrosmanol is a phenolic diterpene that is isolated from Salvia chamelaeagnea. 7-Ethoxyrosmanol has antioxidant activity in vitro and antitumor effects on neuroblastoma cells. 7-Ethoxyrosmanol alleviates hyperglycemia-induced endothelial cell dysfunction via regulating FBXL7. | ||||||||||||||||||||
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20-Deoxocarnosol | 98.0% | 20-Deoxocarnosol (compound 7) is a potent anti-cancer agent that can be found in the roots of Salvia deserta. 20-Deoxocarnosol shows cytotoxicity in cancer cells. | ||||||||||||||||||||
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Carnosol | 98.79% | Carnosol is a potent Ribosomal S6 Kinase (RSK2) inhibitor that could be useful for treating gastric cancer, with an IC50 of ~5.5 μM. Carnosol, a Nrf2 activator, increases the nuclear levels of Nrf2 and can promote the expression of heme oxygenase 1 (HMOX1). | ||||||||||||||||||||
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Dimethyl isorosmanol | Dimethyl isorosmanol (11,12-Di-O-methylisorosmanol) is a compound that can be isolated form Rosmarinus officinalis. Dimethyl isorosmanol has antioxidant activity. | |||||||||||||||||||||
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7-O-Ethylepirosmanol | 7-O-Ethylepirosmanol (Epirosmanol ethyl ether) (Compound 6b) is the derivative of Epirosmanol (HY-111898). 7-O-Ethylepirosmanol is the degradation product of Carnosol (HY-N0643), the main antioxidant component in rosemary. | |||||||||||||||||||||
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6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene | 6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene (Compound 6) is a diterpenoid found in Premna obtusifolia with antibacterial activity. 6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene can significantly inhibit the release of the inflammatory mediator NO, with an IC50 value of 29.1 μM. 6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene can be used for the researches of infection and inflammation. | |||||||||||||||||||||
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6-Epidemethylesquirolin D | 6-Epidemethylesquirolin D (6-epi-O-Demethylesquirolin D) is a Diterpenoids product that can be isolated from the herbs of Euphorbia ehracteolata. | |||||||||||||||||||||
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Isorosmanol | 99.66% | Isorosmanol is an abietane-type diterpene isolated from Rosmarinus officinalis L. aerial parts, with antioxidant, neuroprotective and neurotrophic effects. Isorosmanol inhibits AChE activity and melanin synthesis. | ||||||||||||||||||||
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