83-45-4
Chemical Structure
Sitostanol
Synonym(s): Stigmastanol; 24α-Ethyl cholestanol
- CAS No.: 83-45-4
- Formula:C29H52O
- Molecular Weight:416.72
IUPAC Name: (3S,5S,8R,9S,10S,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-ol
InChIKey: LGJMUZUPVCAVPU-HRJGVYIJSA-N
SMILES: CC[C@H](CC[C@@H](C)[C@]1([H])[C@]2(C)[C@](CC1)([H])[C@]3([H])CC[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC2)C(C)C
Biological Activity: Stigmastanol is a 6-amino derivative. Stigmastanol can be isolated from Hypericum riparium. Stigmastanol increases the secretion of IL-2 and IL-10. Stigmastanol reduces the maximum mitochondrial respiration of cells. Stigmastanol has beneficial effects on the weakened immune function of asthma[1][2][3][4].
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Sitostanol | 99.0% | Stigmastanol is a 6-amino derivative. Stigmastanol can be isolated from Hypericum riparium. Stigmastanol increases the secretion of IL-2 and IL-10. Stigmastanol reduces the maximum mitochondrial respiration of cells. Stigmastanol has beneficial effects on the weakened immune function of asthma. | ||||||||||||||||||||
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Sitostanol (Standard) | ≥98% | Stigmastanol (Standard) is the analytical standard of Stigmastanol. This product is intended for research and analytical applications. Stigmastanol is a 6-amino derivative. Stigmastanol can be isolated from Hypericum riparium. Stigmastanol increases the secretion of IL-2 and IL-10. Stigmastanol reduces the maximum mitochondrial respiration of cells. Stigmastanol has beneficial effects on the weakened immune function of asthma. | ||||||||||||||||||||
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- [1]. Pinhas H, et al. 6-amino derivatives of stigmastanol and cholestanol. J Med Chem. 1971;14(11):1048-1049. [Content Brief]
- [2]. Tanemossu SA, et al. Rare biscoumarin derivatives and flavonoids from Hypericum riparium. Phytochemistry. 2014;105:171-177. [Content Brief]
- [3]. Nascimento EBM, et al. In vitro effects of sitosterol and sitostanol on mitochondrial respiration in human brown adipocytes, myotubes and hepatocytes. Eur J Nutr. 2020 Aug;59(5):2039-2045. [Content Brief]
- [4]. Brüll F, et al. Beneficial effects of sitostanol on the attenuated immune function in asthma patients: results of an in vitro approach. PLoS One. 2012;7(10):e46895. [Content Brief]
Keywords
