83459-41-0
Chemical Structure
Ginsenoside Ra1
- CAS No.: 83459-41-0
- Formula:C58H98O26
- Molecular Weight:1211.38
IUPAC Name: (2R,3S,4S,5R,6S)-2-((((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-6-(((S)-2-((3S,5R,8R,9R,10R,12R,13R,14R,17S)-3-(((2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-12-hydroxy-4,4,8,10,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-methylhept-5-en-2-yl)oxy)tetrahydro-2H-pyran-3,4,5-triol
InChIKey: KVMXBSSOCCPAOR-WWJNHZDPSA-N
SMILES: C[C@]12[C@]3([C@@]([C@H](O)C[C@]1([H])[C@@]4([C@@](C(C)([C@@H](O[C@@]5([H])[C@@H]([C@H]([C@H](O)[C@@H](CO)O5)O)O[C@]6([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)CO)CC4)C)([H])CC2)C)([H])[C@]([C@@](CC/C=C(C)/C)(C)O[C@@H]7O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)CO[C@H]8[C@@H]([C@H]([C@@H](O[C@@]9([H])[C@@H]([C@H]([C@H](O)CO9)O)O)CO8)O)O)([H])CC3)C
Biological Activity: Ginsenoside Ra1 is a dammarane-type bisdesmosidic saponin present in the roots of Panax ginseng. Ginsenoside Ra1 is hydrolyzed by gut-derived β-D-xylosidase to Ginsenoside Rb2 (HY-N0040). Ginsenoside Ra1 inhibits hypoxia/reoxygenation-induced activation of protein tyrosine kinase (PTK)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ginsenoside Ra1 | 99.88% | Ginsenoside Ra1 is a dammarane-type bisdesmosidic saponin present in the roots of Panax ginseng. Ginsenoside Ra1 is hydrolyzed by gut-derived β-D-xylosidase to Ginsenoside Rb2 (HY-N0040). Ginsenoside Ra1 inhibits hypoxia/reoxygenation-induced activation of protein tyrosine kinase (PTK). | ||||||||||||||||||||
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References
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[1]. Koizumi H, et al. Studies on the Saponins of Ginseng. IV. On the Structure and Enzymatic Hydrolysis of Ginsenoside-Ra1. Chemical and Pharmaceutical Bulletin, 1982, 30(7): 2393-2398.
- [2]. Dou DQ, et al. The inhibitory effects of ginsenosides on protein tyrosine kinase activated by hypoxia/reoxygenation in cultured human umbilical vein endothelial cells. Planta Med. 2001 Feb;67(1):19-23. [Content Brief]
