852702-51-3
Chemical Structure
MSNBA
- CAS No.: 852702-51-3
- Formula:C14H12N2O6S
- Molecular Weight:336.32
IUPAC Name: N-(4-(methylsulfonyl)-2-nitrophenyl)benzo[d][1,3]dioxol-5-amine
InChIKey: FUVYUOPHDIDJOP-UHFFFAOYSA-N
SMILES: O=[N+](C1=CC(S(=O)(C)=O)=CC=C1NC2=CC3=C(OCO3)C=C2)[O-]
Biological Activity: MSNBA is a potent and selective GLUT5 fructose transport inhibitor with an IC50 of 0.10 mM. MSNBA does not affect the transport activity of human GLUT1, GLUT2, GLUT3, GLUT4 or bacterial GlcPSe. MSNBA competitively inhibits GLUT5 fructose uptake with a Ki of 3.2 μM in MCF7 cells. MSNBA can be used for the study of cancer or diabetes[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
MSNBA | 97.39% | MSNBA is a potent and selective GLUT5 fructose transport inhibitor with an IC50 of 0.10 mM. MSNBA does not affect the transport activity of human GLUT1, GLUT2, GLUT3, GLUT4 or bacterial GlcPSe. MSNBA competitively inhibits GLUT5 fructose uptake with a Ki of 3.2 μM in MCF7 cells. MSNBA can be used for the study of cancer or diabetes. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords