869288-64-2
869288-64-2
Chemical Structure
PF-573228
- CAS No.: 869288-64-2
- Formula:C22H20F3N5O3S
- Molecular Weight:491.49
IUPAC Name: 6-((4-((3-(methylsulfonyl)benzyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-3,4-dihydroquinolin-2(1H)-one
InChIKey: HESLKTSGTIBHJU-UHFFFAOYSA-N
SMILES: O=C1NC2=C(C=C(NC3=NC=C(C(F)(F)F)C(NCC4=CC=CC(S(=O)(C)=O)=C4)=N3)C=C2)CC1
Biological Activity: PF-573228 is a potent and selective FAK inhibitor with IC50 of 4 nM for purified recombinant catalytic fragment of FAK.
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PF-573228 | 99.32% | PF-573228 is a potent and selective FAK inhibitor with IC50 of 4 nM for purified recombinant catalytic fragment of FAK. | ||||||||||||||||||||
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PF-573228 (Standard) | ≥98% | PF-573228 (Standard) is the analytical standard of PF-573228. This product is intended for research and analytical applications. PF-573228 is a potent and selective FAK inhibitor with IC50 of 4 nM for purified recombinant catalytic fragment of FAK. | ||||||||||||||||||||
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Keywords
