94-07-5
94-07-5
Chemical Structure
Synephrine
Synonym(s): Oxedrine
- CAS No.: 94-07-5
- Formula:C9H13NO2
- Molecular Weight:167.21
IUPAC Name: 4-(1-hydroxy-2-(methylamino)ethyl)phenol
InChIKey: YRCWQPVGYLYSOX-UHFFFAOYSA-N
SMILES: OC(C1=CC=C(O)C=C1)CNC
Biological Activity: Synephrine (Oxedrine), an alkaloid, is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium. Synephrine is a sympathomimetic compound and can be used for weight loss[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Synephrine | 98.0% | Synephrine (Oxedrine), an alkaloid, is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium. Synephrine is a sympathomimetic compound and can be used for weight loss. | ||||||||||||||||||||
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Synephrine (Standard) | ≥98% | Synephrine (Standard) is the analytical standard of Synephrine. This product is intended for research and analytical applications. Synephrine (Oxedrine), an alkaloid, is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium. Synephrine is a sympathomimetic compound and can be used for weight loss. | ||||||||||||||||||||
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p-Synephrine | 99.90% | p-Synephrine is an orally active alkaloid dietary supplement without indirect sympathomimetic activity or cardiovascular stimulatory activity. p-Synephrine stimulates AMPK phosphorylation and mediates Glut4 translocation to increase glucose consumption and lactate production in skeletal muscle cells. p-Synephrine also downregulates the p38 MAPK and NF-κB signaling pathways to inhibit pro-inflammatory cytokine production and alter oxidative metabolism. p-Synephrine exhibits low subchronic toxicity in mice. p-Synephrine can be applied to research related to systemic inflammatory response syndrome, obesity, and type 2 diabetes. | ||||||||||||||||||||
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Phenylephrine hydrochloride (Standard) | 99.68% | Phenylephrine (hydrochloride) (Standard) is the analytical standard of Phenylephrine (hydrochloride). This product is intended for research and analytical applications. (R)-(-)-Phenylephrine hydrochloride is a selective α1-adrenoceptor agonist with pKis of 5.86, 4.87 and 4.70 for α1D, α1B and α1A receptors respectively. | ||||||||||||||||||||
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Octopamine | 99.93% | Octopamine ((±)-p-Octopamine) is an orally active neurotransmitter and neuromodulator that can cross the blood-brain barrier. Octopamine activates octopamine receptors (octopamine receptor), G protein-coupled/Gαs-coupled receptors (G protein-coupled/Gαs-coupled receptor), adenylyl cyclase (adenylyl cyclase)/cAMP, calcium, and hyperpolarizing conductance increases. Octopamine can be used in research on various neurological diseases, metabolic diseases, and cardiovascular and cerebrovascular diseases. | ||||||||||||||||||||
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Phenylephrine (Standard) | 99.96% | Phenylephrine (Standard) is the analytical standard of Phenylephrine. This product is intended for research and analytical applications. (R)-(-)-Phenylephrine is a selective α1-adrenoceptor agonist primarily used as a decongestant. | ||||||||||||||||||||
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Synephrine hydrochloride (Standard) | 99.56% | Synephrine (hydrochloride) (Standard) is the analytical standard of Synephrine (hydrochloride). This product is intended for research and analytical applications. Synephrine (Oxedrine) hydrochloride, an alkaloid, is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium. Synephrine hydrochloride is a sympathomimetic compound and can be used for weight loss. | ||||||||||||||||||||
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(R)-Octopamine | 95.22% | (R)-Octopamine is a Gs-coupled receptor agonist. (R)-Octopamine binds to the orthosteric site of BmOAR2 and interacts with the Asp115, Ser202 and Tyr300 residues to activate the receptor, which couples to Gs protein and thereby stimulates adenylate cyclase activity. | ||||||||||||||||||||
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DL-Phenylephrine hydrochloride | DL-Phenylephrine ((±)-Phenylephrine) hydrochloride is a selective agonist of the alpha1-adrenergic receptor, exhibiting potent vasoconstrictive activity. | |||||||||||||||||||||
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(S)-1-(4-Hydroxyphenyl)ethane-1,2-diol | (S)-1-(4-Hydroxyphenyl)ethane-1,2-diol is an active constituent of the aerial parts of Angelica sinensis. (S)-1-(4-Hydroxyphenyl)ethane-1,2-diol significantly inhibits the growth of Aeromonas hydrophila. Anticoagulative and antibiotic activities. | |||||||||||||||||||||
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Deterenol hydrochloride | 99.74% | Deterenol hydrochloride (AL842) is a selective beta-agonist. Deterenol hydrochloride causes vasodepressor, anxiety, increasing heart rate, hypotension palpitation and respiratory distress. | ||||||||||||||||||||
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Salbutamol impurity 5 | Salbutamol impurity 5 is an impurity of Salbutamol. | |||||||||||||||||||||
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References
- [1]. Thomas JE, et al. STEMI in a 24-year-old man after use of a synephrine-containing dietary supplement: a case report and review of the literature. Tex Heart Inst J. 2009;36(6):586-90. [Content Brief]
- [2]. Huang YT, et al. Hemodynamic effects of synephrine treatment in portal hypertensive rats. Jpn J Pharmacol. 2001 Feb;85(2):183-8. [Content Brief]
