99754-06-0
99754-06-0
Chemical Structure
ONO-RS-082
- CAS 番号: 99754-06-0
- Formula:C21H22ClNO3
- Molecular Weight:371.86
IUPAC Name: (E)-4-chloro-2-(3-(4-pentylphenyl)acrylamido)benzoic acid
InChIKey: MDVFITMPFHDRBZ-JLHYYAGUSA-N
SMILES: ClC1=CC(NC(/C=C/C2=CC=C(C=C2)CCCCC)=O)=C(C=C1)C(O)=O
Biological Activity: ONO-RS-082 is an inhibitor of phospholipase A (PLA)[1]. ONO-RS-082 inhibits PLA2 with the IC50 of 1.0 μM, but does not inhibit PLC even at 100 μM[2].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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ONO-RS-082 | 99.31% | ONO-RS-082 is an inhibitor of phospholipase A (PLA). ONO-RS-082 inhibits PLA2 with the IC50 of 1.0 μM, but does not inhibit PLC even at 100 μM. | ||||||||||||||||||||
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References
- [1]. H S Banga,et al. Activation of phospholipases A and C in human platelets exposed to epinephrine: role of glycoproteins IIb/IIIa and dual role of epinephrine. Proc Natl Acad Sci U S A.1986 Dec;83(23):9197-201. [Content Brief]
- [2]. H Ohno, et al. Effect of phospholipase A2 inhibitors on mouse T lymphocytes. I. Phospholipase A2 inhibitors exert similar immunological activities as glycosylation inhibiting factor. Int Immunol. 1989;1(4):425-33. [Content Brief]
Keywords
