Catestatin sCst
Catestatin sCst is a negative control peptide with a scrambled amino acid sequence. Catestatin sCst fails to activate human mast cells and is used to verify the specificity of Catestatin action.
For research use only. We do not sell to patients.
- Formula: C104H164N32O27S
- Molecular Weight:2326.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Catestatin sCst (2500 nM-5 μM; 40 min) does not induce degranulation of LAD2 human mast cells or human peripheral blood-derived mast cells[1].
Catestatin sCst (10 μM; 30 min) does not induce release of LTC4, PGD2, or PGE2 from LAD2 human mast cells[1].
Catestatin sCst (10 μM; 6 hr) does not induce protein production of GM-CSF, MCP-1/CCL2, MIP-1α/CCL3, or MIP-1β/CCL4 in LAD2 human mast cells[1].
Catestatin sCst (0.32 μM; 3 hr) does not induce chemotaxis of LAD2 human mast cells[1].
Catestatin sCst (5 μM; 5 min) does not induce phosphorylation of ERK, JNK, or p38 MAPKs in LAD2 human mast cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:LAD2 human mast cell line
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Concentration:10 μM
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Incubation Time:6 hr
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Result:Exerted no effect on protein production of GM-CSF, MCP-1/CCL2, MIP-1α/CCL3, or MIP-1β/CCL4 from LAD2 cells.
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Cell Line:LAD2 human mast cell line
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Concentration:5 μM
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Incubation Time:5 min
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Result:Exerted no effect on phosphorylation of ERK, JNK, or p38 MAPKs in LAD2 cells.
Chemical Information
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Molecular Weight 2326.68
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Formula C104H164N32O27S
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SMILES
O=C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(NCC(N4[C@@H](CCC4)C(NCC(N5[C@@H](CCC5)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCSC)N
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Sequence
Met-Lys-Leu-Ser-Ser-Ser-Phe-Arg-Ala-Tyr-Ala-Arg-Gly-Phe-Arg-Gly-Pro-Gly-Pro-Gln-Leu
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Sequence Shortening
MKLSSSFRAYARGFRGPGPQL
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Catestatin sCst Related Classifications
HY-P3395A Related Classifications
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- Catestatin sCst
- PERK
- JNK
- p38 MAPK
- extracellular signal-regulated kinase
- human mast cells
- macrophage inflammatory protein-1a/CCL3
- macrophage inflammatory protein-1b/CCL4
- prostaglandin E2
- monocyte chemotactic protein-1/CCL2
- leukotriene C4
- granulocyte-macrophage colony-stimulating factor
- c-Jun N-terminal kinase
- prostaglandin D2
- Inhibitor
- inhibitor
- inhibit