CCG 258001
CCG 258001 is a GRK inhibitor with IC50 values of 0.29, 51.8, and 33 µM against GRK2, GRK1, and GRK5, respectively. CCG 258001 inhibits GRK activity in cardiomyocytes and other muscle cells. CCG 258001 is applicable to the research of heart diseases, including heart failure, myocardial hypertrophy, and hypertension.
For research use only. We do not sell to patients.
- CAS No.: 2055990-96-8
- Formula: C20H22FN3O
- Molecular Weight:339.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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GRK2 0.29 μM (IC50) |
GRK5 33 μM (IC50) |
CCG 258001 (5 min) potently inhibits GRK2 with an IC50 of 0.29 µM, while it shows weak inhibitory effects on GRK1 and GRK5[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2055990-96-8
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Molecular Weight 339.41
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Formula C20H22FN3O
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SMILES
C(OC=1C=C2C(=CC1)NN=C2)[C@H]3[C@@H](CCN(C)C3)C4=CC=C(F)C=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CCG 258001 Related Classifications
HY-120168 Related Classifications
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