CDC14A/B-IN-2
CDC14A/B-IN-2, phosphotyrosine mimetic, is a competitive human CDC14A/B phosphatase inhibitor with IC50 values of 10.4 and 11.2 μM, and Ki values of 5.8 and 7.3 μM. CDC14A/B-IN-2 shows at least 20-fold selectivity over other protein tyrosine phosphatases. CDC14A/B-IN-2 can be used for the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 3048654-21-0
- Formula: C13H9F2O4P
- Molecular Weight:298.18
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
hCDC14A 10.4 μM (IC50) |
hCDC14B 11.2 μM (IC50) |
hCDC14A 5.8 μM (Ki) |
hCDC14B 7.3 μM (Ki) |
CDC14A/B-IN-2 (Compound 9) (10 min) competitively inhibits recombinant human CDC14A and CDC14B phosphatases with IC50 values of 10.4 and 11.2 μM, and Ki values of 5.8 and 7.3 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 3048654-21-0
-
Molecular Weight 298.18
-
Formula C13H9F2O4P
-
SMILES
O=P(O)(C(F)(C1=C2C3=C(C=CC=C3)OC2=CC=C1)F)O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)