Ezetimibe-d4
Based on 1 Customer Validation
Ezetimibe-d4 (SCH 58235-d4) is the deuterium labeled Ezetimibe (HY-17376). Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.14%
- CAS. Nr.: 1093659-90-5
- Formel: C24H17D4F2NO3
- Molecular Weight:413.45
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1093659-90-5
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Unlabeled Cas 163222-33-1
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Appearance Solid
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Molecular Weight 413.45
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Formel C24H17D4F2NO3
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Color White to off-white
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SMILES
O=C1[C@H](CC[C@H](O)C2=CC=C(F)C=C2)[C@@H](C3=CC=C(O)C=C3)N1C(C([2H])=C4[2H])=C([2H])C([2H])=C4F
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Synonyms
SCH 58235-d4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 200 mg/mL (483.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 0.1 mg/mL (0.24 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (247 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4187 mL | 12.0934 mL | 24.1867 mL | 60.4668 mL |
| 5 mM | 0.4837 mL | 2.4187 mL | 4.8373 mL | 12.0934 mL | |
| 10 mM | 0.2419 mL | 1.2093 mL | 2.4187 mL | 6.0467 mL | |
| 15 mM | 0.1612 mL | 0.8062 mL | 1.6124 mL | 4.0311 mL | |
| 20 mM | 0.1209 mL | 0.6047 mL | 1.2093 mL | 3.0233 mL | |
| 25 mM | 0.0967 mL | 0.4837 mL | 0.9675 mL | 2.4187 mL | |
| 30 mM | 0.0806 mL | 0.4031 mL | 0.8062 mL | 2.0156 mL | |
| 40 mM | 0.0605 mL | 0.3023 mL | 0.6047 mL | 1.5117 mL | |
| 50 mM | 0.0484 mL | 0.2419 mL | 0.4837 mL | 1.2093 mL | |
| 60 mM | 0.0403 mL | 0.2016 mL | 0.4031 mL | 1.0078 mL | |
| 80 mM | 0.0302 mL | 0.1512 mL | 0.3023 mL | 0.7558 mL | |
| 100 mM | 0.0242 mL | 0.1209 mL | 0.2419 mL | 0.6047 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Ezetimibe-d4 Related Classifications
HY-17376S Related Classifications
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