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Maraviroc

(Synonyms: UK-427857)
59 Cited Publications
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Based on 59 publication(s) in Google Scholar

Maraviroc (UK-427857) is a selective CCR5 antagonist with activity against human HIV.

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  • Reinheit: 99.98%
  • CAS. Nr.: 376348-65-1
  • Formel: C29H41F2N5O
  • Molecular Weight:513.67
  • Speicherung:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Maraviroc Chemical Structure
    Maraviroc Chemical Structure
  • Experimental Validation Results for Maraviroc
  • Experimental Validation Results for Maraviroc
  • Experimental Validation Results for Maraviroc
  • Experimental Validation Results for Maraviroc
  • Experimental Validation Results for Maraviroc
CAS. Nr.: 376348-65-1
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In Vivo Efficacy StudyCell Migration/Invasion AssayIHCWB
  • Cell Migration/Invasion Assay
  • In Vivo Efficacy Study
  • IHC
  • In Vivo Efficacy Study
  • WB

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  • Maraviroc Chemical Structure
    Maraviroc Chemical Structure
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    Maraviroc purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jul 21:e00950. [Abstract]

    Customer Validation
     Freshly isolated neutrophils were pre-treated overnight with culture supernatant from AGS or AGS-EBV cells (H), supplemented with Maraviroc (1 µM).

  • 1/16

    Maraviroc purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jun 19:e16476. [Abstract]

    Customer Validation
     LLC‐Vector and LLC‐ENH‐OV tumor growth in mice treated with or without maraviroc (i.p., 10 mg/kg, every other day).

  • 1/16

    Maraviroc purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jun 19:e16476. [Abstract]

    Customer Validation
     Representative images of IF staining for CD31 and IHC staining for F4/80 in LLC‐Vector and LLC‐ENH‐OV tumors sections treated with or without maraviroc (i.p., 10 mg kg−1, every other day i.p., 10 mg/kg, every other day ).

  • 1/16

    Maraviroc purchased from MedChemExpress. Usage Cited in: Nat Commun. 2020 Nov 25;11(1):5994. [Abstract]

    Customer Validation
     Aortic diameters in CaCl2-treated mice after maraviroc (intraperitoneally injected with 10 mg/kg , daily for 3 weeks) application (n = 4 each).

  • 1/16

    Maraviroc purchased from MedChemExpress. Usage Cited in: Front Pharmacol. 2017 May 3:8:230. [Abstract]

    Customer Validation
     Inhibition of total and phosphorylation levels of CCR5, PKC δ, and p38 in MIP-1β-induced U937 cells by WTD. Cells are pretreated with PMA for 48 h and then incubated with or without WTD or MVC for 2 h. Subsequently, cells are stimulated with MIP-1β (25 nM). After 10 min of stimulation, cells are collected to detect total and phosphorylated (p) CCR5 (A), PKC δ (B), and p38 (C) by western blotting.

  • Maraviroc