AChE-IN-104
AChE-IN-104 (compound 3e) is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 8.01 µM. AChE-IN-104 also inhibits BChE and MAO-A with IC50s of 65.41 µM and 1.51 µM, respectively. AChE-IN-104 can be used for Alzheimer’s disease (AD) research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C20H15F3N2O4
- Molecular Weight:404.34
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
MAO-A 1.51 μM (IC50) |
AChE 8.01 μM (IC50) |
BChE 65.41 μM (IC50) |
Chemical Information
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Molecular Weight 404.34
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Formel C20H15F3N2O4
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SMILES
COC1=C(OC(C(/C(C)=N/NC(C2=CC=C(C(F)(F)F)C=C2)=O)=C3)=O)C3=CC=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)