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Art. -Nr.: HY-W753557

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Avocadene

Avocadene is a natural product isolated from Persea americana leaves, with anticancer, insecticidal, anti-Helicobacter pylori, and anti-inflammatory activity. Avocadene exerts antibacterial and anti‑inflammatory effects by suppressing Helicobacter pylori growth and inhibiting protein denaturation. Avocadene displays obvious cytotoxic activity against human prostate cancer PC‑3 cells with an IC₅₀ of 0.5 μg/mL. Avocadene can be used for research of Helicobacter pylori‑associated gastrointestinal inflammation, gastroduodenal injury and prostate tumors.

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CAS. Nr.: 24607-08-7
Formel: C₁₇H₃₄O₃
Molecular Weight:286.45

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Avocadene Chemical Structure

CAS. Nr.: 24607-08-7

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Avocadene exhibits cytotoxic activity against human prostate adenocarcinoma (PC-3) cells with an IC₅₀ of 0.5 µg/mL^[1].
Avocadene exhibits insecticidal activity against yellow fever mosquito larvae with an LC₅₀ of 0.2 µg/mL^[1].
Avocadene exhibits strong anti-Helicobacter pylori activity, with an inhibition zone of 12.9 mm and a minimum inhibitory concentration of 32 μg/mL^[2].
Avocadene exhibits notable anti-inflammatory activity, inhibiting protein denaturation by 22.40% in vitro^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 24607-08-7
Molecular Weight 286.45
Formel C₁₇H₃₄O₃
SMILES

C=CCCCCCCCCCCC[C@@H](O)C[C@@H](O)CO
Structure Classification
- Others
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Cunha VLS. De Novo Asymmetric Synthesis of Avocadyne, Avocadene and Avocadane Stereoisomers. J Org Chem. 2019;84(21):13898-13904.

[2]. Le TNC. Anti-Helicobacter pylori and anti-inflammatory activities of Persea americana leaf extract and its isolated avocadene: a promising natural therapeutic candidate. Nat Prod Res. 2025; Epub ahead of print.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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