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Art. -Nr.: HY-182718

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AZD0011-PL

AZD0011-PL is a human arginase 1/ 2 inhibitor with IC₅₀ values of 0.01 μM and 0.02 μM. AZD0011-PL can be used for the researches of cancer, respiratory inflammatory disease.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 2374807-39-1
Formel: C₉H₁₉BN₂O₄
Molecular Weight:230.07

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

AZD0011-PL Chemical Structure

CAS. Nr.: 2374807-39-1

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

AZD0011-PL is a human arginase 1/ 2 inhibitor with IC₅₀ values of 0.01 μM and 0.02 μM. AZD0011-PL can be used for the researches of cancer, respiratory inflammatory disease^[1].

IC₅₀ & Target^[1]

hArginase 1

0.01 μM (IC₅₀)

hArginase 2

0.02 μM (IC₅₀)

In Vitro

AZD0011-PL (Compound 7) potently inhibits recombinant human Arginase 1 with an IC₅₀ of 0.01 μM and recombinant human Arginase 2 with an IC₅₀ of 0.02 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2374807-39-1
Molecular Weight 230.07
Formel C₉H₁₉BN₂O₄
SMILES

OB(O)CCCC[C@]1(NC[C@@H](C1)N)C(O)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Scott Nathan MLYNARSKI, et al. Arginase inhibitors and methods of use thereof. WO2019159120A1. 2020-08-17

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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