Art. -Nr.: HY-125865

Casein

2 Cited Publications

Kundenbewertung

Based on 2 publication(s) in Google Scholar

Casein is an orally active phosphoprotein that can be separated into various electrophoretic components, such as α₂-Casein, κ-Casein, β-casein, and γ-casein. Casein has also been blended and grafted with other polymers, cross-linkers, or monomers to improve its functional properties. Casein enhances calcium absorption and reduces the extent of fissure as well as smooth-surface caries. Casein promotes proliferation of prostate cancer. Casein has various applications in the paper, leather, textile, and food industries, serving as coatings, adhesives, and packaging materials.

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Reinheit: 97.40%
CAS. Nr.: 9000-71-9
Formel: C₈₁H₁₂₅N₂₂O₃₉P
Molecular Weight:2061.96

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Casein Chemical Structure

CAS. Nr.: 9000-71-9

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Biologische Aktivität
- Beschreibung
- In Vitro
- In Vivo
- Clinical Trial
Chemical Information
Publications (2)
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle Casein Kinase Isoform-spezifische Produkte anzeigen :

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen :

In Vitro

Casein (1 mg/mL) promotes proliferation of prostate cancer cells PC3 (166%) and LNCaP (142%)^[2].
Casein (0.2%) supports cell density-dependent growth of Myxococcus xanthus^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Casein (hydrolyzed, 16-32 energy percent protein, diet, p.o.) reduces diet-induced obesity in male C57BL/6J mice^[4].
Casein (500 ppm, p.o., 2 weeks) enhances calcium absorption in the rat^[5].
Casein (2% (w/v), in drinking water, p.o.) reduces the extent of fissure and smooth-surface caries of male Sprague-Dawley rats consuming a solid cariogenic diet^[6].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS. Nr. 9000-71-9
Appearance Solid
Molecular Weight 2061.96
Formel C₈₁H₁₂₅N₂₂O₃₉P
Color Off-white to yellow
SMILES

[Casein]
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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Int J Biol Macromol

Dynamic catalytic domain plasticity governs substrate specificity in industrial serine proteases: Structural and functional implications. [Abstract]

2025 Oct 17;331(Pt 1):148374. PMID: 41110577
Talanta

Phenylboronic acid decorated SiO2@Fe3O4 magnetic nanoparticle coupled with peroxidase-like Au,Pt,Cu@polydopamine immunoprobe based sandwich approach for the detection of transferrin. [Abstract]

2025 Aug 26;297(Pt B):128747. PMID: 40885136

Casein purchased from MedChemExpress. Usage Cited in: Talanta. 2025 Aug 26;297(Pt B):128747. [Abstract]

Adsorption performance of PBA-SiO₂@Fe₃O₄ toward TRF after blocking with different concentrations of Casein (0.1 %-1 %).

Casein purchased from MedChemExpress. Usage Cited in: Talanta. 2025 Aug 26;297(Pt B):128747. [Abstract]

Adsorption performance of PBA-SiO₂@Fe₃O₄ toward TRF after blocking with Casein (1 %).

Casein purchased from MedChemExpress. Usage Cited in: Talanta. 2025 Aug 26;297(Pt B):128747. [Abstract]

Adsorption performance of PBA-SiO₂@Fe₃O₄ toward various glycoproteins utilizingCasein (1 %).

Casein purchased from MedChemExpress. Usage Cited in: Talanta. 2025 Aug 26;297(Pt B):128747. [Abstract]

Adsorption performance of PBA-SiO₂@Fe₃O₄ toward various glycoproteins utilizingCasein (0.1 %-1 %).

Casein purchased from MedChemExpress. Usage Cited in: Talanta. 2025 Aug 26;297(Pt B):128747. [Abstract]

Casein (0.1 %; 400 μL) did not occupy the PBA binding sites responsible for interaction with sugar residues in TRF, as suggested by the negligible impact of increasing glucose concentrations on its blocking effect.

Lösungsmittel & Löslichkeit

In Vitro:

0.1 M NaOH : 20 mg/mL (9.70 mM; ultrasonic and warming and heat to 60°C)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

0.4850 mL

2.4249 mL

4.8498 mL

5 mM

0.0970 mL

0.4850 mL

0.9700 mL

10 mM

---

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Ghosh A, et al. Effect of cross-linking on microstructure and physical performance of casein protein. Biomacromolecules. 2009;10(7):1681-1688. [Content Brief]

[2]. Park SW, et al. A milk protein, casein, as a proliferation promoting factor in prostate cancer cells. World J Mens Health. 2014 Aug;32(2):76-82. [Content Brief]

[3]. Rosenberg E, et al. Cell density-dependent growth of Myxococcus xanthus on casein. J Bacteriol. 1977 Feb;129(2):770-7. [Content Brief]

[4]. Lillefosse HH, et al. Hydrolyzed casein reduces diet-induced obesity in male C57BL/6J mice. J Nutr. 2013 Sep;143(9):1367-75. [Content Brief]

[5]. Bennett T, et al. The effect of high intakes of casein and casein phosphopeptide on calcium absorption in the rat. Br J Nutr. 2000 Jun;83(6):673-80. [Content Brief]

[6]. Reynolds EC, et al. Effect of casein and whey-protein solutions on caries experience and feeding patterns of the rat. Arch Oral Biol. 1984;29(11):927-33. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
0.1 M NaOH	1 mM	0.4850 mL	2.4249 mL	4.8498 mL	12.1244 mL
0.1 M NaOH	5 mM	0.0970 mL	0.4850 mL	0.9700 mL	2.4249 mL

Keywords

Casein

2 Cited Publications

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Casein

Drug Repurposing Compound Library Plus

Clinical Compound Library Plus

Cosmetic Ingredient Compound Library

Publications Citing Use of MedChemExpress (MCE) Casein

Alle Casein Kinase Isoform-spezifische Produkte anzeigen

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Publications (2)

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

Casein

Drug Repurposing Compound Library Plus

Clinical Compound Library Plus

Cosmetic Ingredient Compound Library

Publications Citing Use of MedChemExpress (MCE) Casein

Alle Casein Kinase Isoform-spezifische Produkte anzeigen

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Publications (2)

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

Casein Related Classifications

HY-125865 Related Classifications