CHBO4
CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. CHBO4 reduce cell damage by scavenging intracellular reactive oxygen species (ROS). CHBO4 can be used for Parkinson's Disease (PD) research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 98991-32-3
- Formel: C15H10BrFO
- Molecular Weight:305.14
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
|
hMAO-B 0.031 μM (IC50) |
hMAO-B 0.010 μM (Ki) |
CHBO4 (10-500 µg/mL, 48 h) is biologically safe in Vero cells[1].
CHBO4 (128.8 µg/mL, 10 min) can reduce ROS generation in Vero cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:Vero cells
-
Concentration:10-500 µg/mL
-
Incubation Time:48 h
-
Result:Reduced cell viability percentage with the IC50 value of 128.8 µg/mL
Decreased cellular density, cellular shrinkage, and blebbing exposed to concentrations (100-300 µg/mL) in Vero cells
Chemical Information
-
CAS. Nr. 98991-32-3
-
Molecular Weight 305.14
-
Formel C15H10BrFO
-
SMILES
BrC1=CC=C(C(/C=C/C2=CC=C(F)C=C2)=O)C=C1
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CHBO4 Related Classifications
HY-155137 Related Classifications
Powered by Bioz