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Art. -Nr.: HY-134648

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Ganfeborole

Name: Ganfeborole
Brand: MedChemExpress
SKU: HY-134648
Availability: PreOrder

(Synonyms: GSK656 free base; GSK3036656 free base; GSK070 free base)

5 Cited Publications

Kundenbewertung

Based on 5 publication(s) in Google Scholar

Ganfeborole (GSK656 free base) is a potent, selective and orally active inhibitor of M. tuberculosis leucyl-tRNA synthetase, with an IC₅₀ of 0.20 μM. Ganfeborole can be used for the research of tuberculosis.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 2131798-12-2
Formel: C₁₀H₁₃BClNO₄
Molecular Weight:257.48

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Ganfeborole Chemical Structure

CAS. Nr.: 2131798-12-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

Chemical Information

CAS. Nr. 2131798-12-2
Molecular Weight 257.48
Formel C₁₀H₁₃BClNO₄
SMILES

OB1O[C@H](CN)C2=C(Cl)C=CC(OCCO)=C21
Synonyms

GSK656 free base; GSK3036656 free base; GSK070 free base
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (5)

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Nat Nanotechnol

Nanofibrous supramolecular peptide hydrogels for controlled release of small-molecule drugs and biologics. [Abstract]

2025 Oct;20(10):1502-1513. PMID: 40931056
Antimicrob Agents Chemother

A Novel Leucyl-tRNA Synthetase Inhibitor, MRX-6038, Expresses Anti-Mycobacterium abscessus Activity In Vitro and In Vivo. [Abstract]

2022 Sep 20;66(9):e0060122. PMID: 35969055
Biofuel Bioprod Bior

2025 Sep 3;19(5):1378-1399.
ACS Chem Biol

Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents. [Abstract]

2022 Jan 21;17(1):39-53. PMID: 34908399
bioRxiv

2024 May 23.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Li X, et, al. Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656). J Med Chem. 2017 Oct 12;60(19):8011-8026. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

Ganfeborole

5 Cited Publications

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Biologische Aktivität
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Chemical Information
Publications (5)
Reinheit & Dokumentation
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Ganfeborole

Publications Citing Use of MedChemExpress (MCE) Ganfeborole

Biologische Aktivität

Chemical Information

Publications (5)

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Ganfeborole Related Classifications

HY-134648 Related Classifications

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