hAChE-IN-9
hAChE-IN-9 (compound 7i) is a selective inhibitor of human acetylcholinesterase (hAChE) with IC50 of 0.05 μM and 2.85 μM for AChE and BChE, respectively. hAChE-IN-9 modulates toxic Aβ oligomer forms into non-toxic ones and has antioxidant and neuroprotective effects against Aβ-induced toxicity. hAChE-IN-9 can be used for the study of Alzheimer's disease.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C20H15ClN6O4S
- Molecular Weight:470.89
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
hAChE 0.05 μM (IC50) |
hBCHE 2.85 μM (IC50) |
Chemical Information
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Molecular Weight 470.89
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Formel C20H15ClN6O4S
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SMILES
O=C(/C(C#N)=C(SC)/NC1=CC=C([N+]([O-])=O)C=C1)NN2C(CCl)=NC3=CC=CC=C3C2=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)