hCAIX-IN-10
hCAIX-IN-10 (Compound 6i) is a selective carbonic anhydrase IX and XII inhibitor with Ki s of 61.5 and 586.8 nM for hCA IX and hCA XII, respectively. hCA IX and hCA XII are transmembrane isoforms which have been characterized as biomarkers for several types of tumors. The hCA XII assists in maintenance of acid-base homoeostasis in normal as well as tumor cells.
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- CAS. Nr.: 2497504-72-8
- Formel: C28H21N3O3S
- Molecular Weight:479.55
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
IC50 & Target
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CA IX |
In Vitro
Chemical Information
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CAS. Nr. 2497504-72-8
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Molecular Weight 479.55
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Formel C28H21N3O3S
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SMILES
O=C1N(C2=CC=CC(C)=C2)C(C3=CN(C4=CC=CC=C4)N=C3C5=CC6=CC=CC=C6OC5=O)SC1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
hCAIX-IN-10 Related Classifications
HY-147827 Related Classifications
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