LDC0496
LDC0496 is a potent and selective EGFR inhibitor. LDC0496 possesses intense inhibitory potency toward EGFR and Her2 exon20 insertion mutations, as well as selectivity over wild type EGFR and within the kinome.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2411874-83-2
- Formel: C32H35N5O3
- Molecular Weight:537.65
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Alle EGFR Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
IC50: 0.152 ± 0.011 μM in Ba/F3 (EGFR-insNPH), 0.162 ± 0.010 μM in Ba/F3 (Her2-insYVMA), 2.660 ± 0.129 in A431[1]
Chemical Information
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CAS. Nr. 2411874-83-2
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Molecular Weight 537.65
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Formel C32H35N5O3
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SMILES
CC(C=CC(C1=C(NC2=NC=C(C=C21)C(OC(C)C)=O)C3=CC=C(C=C3)N4CCN(CC4)C)=C5)=C5NC(C=C)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
LDC0496 Related Classifications
HY-146262 Related Classifications
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