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Art. -Nr.: HY-N0264R

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Ligustrazine (Standard)

(Synonyms: Chuanxiongzine (Standard); Tetramethylpyrazine (Standard))

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Ligustrazine (Standard) (Chuanxiongzine (Standard)) is the analytical standard of Ligustrazine (HY-N0264). This product is intended for research and analytical applications. Ligustrazine (Chuanxiongzine) is an orally active, blood-brain barrier-permeable alkaloid. It can be isolated from Ligusticum striatum DC. Ligustrazine reduces ROS, upregulates the levels of p-Akt/Akt and p-eNOS/eNOS, and decreases ALT and AST. It inhibits glutamate excitotoxicity, calcium overload, oxidative stress, ischemia-reperfusion injury and atherosclerotic plaque progression, enhances synaptic plasticity, and improves neurological function, cerebral infarct volume and brain water content. Ligustrazine possesses anti-inflammatory, antioxidant, lipid-lowering, endothelial protective and hepatoprotective activities. It can be used in studies related to ischemic stroke, cerebral ischemia-reperfusion injury and atherosclerosis.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Reinheit: 99.99%
CAS. Nr.: 1124-11-4
Formel: C₈H₁₂N₂
Molecular Weight:136.19

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ligustrazine (Standard) Chemical Structure

CAS. Nr.: 1124-11-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Chemical Information
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Calculators
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Product Information

Information

Anwendung

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS. Nr. 1124-11-4
Appearance Solid
Molecular Weight 136.19
Formel C₈H₁₂N₂
Color White to off-white
SMILES

CC1=C(C)N=C(C)C(C)=N1
Synonyms

Chuanxiongzine (Standard); Tetramethylpyrazine (Standard)
Structure Classification
- Others
Initial Source
- Plants
- Umbelliferae
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Verweise

[1]. Wang Z, et al. The protective effects of ligustrazine on ischemic stroke: a systematic review and meta-analysis of preclinical evidence and possible mechanisms. Front Pharmacol. 2024;15:1373663. Published 2024 Mar 13. [Content Brief]

[2]. Ding Y, et al. The protective effect of ligustrazine on rats with cerebral ischemia-reperfusion injury via activating PI3K/Akt pathway. Hum Exp Toxicol. 2019;38(10):1168-1177. [Content Brief]

[3]. Jiang F, et al. Ligustrazine improves atherosclerosis in rat via attenuation of oxidative stress. Pharm Biol. 2011;49(8):856-863. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

MOQ

Minimum order quantity

100 mg

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Product Information

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Ligustrazine (Standard)

Ligustrazine

Pyrazinamide

2-Pyrazinecarboxylic acid (Standard)

2,5-Dimethylpyrazine

Pyrazinamide (Standard)

Pyrazine-2-carbonitrile

Favipiravir

2-Amino-5-bromopyrazine

T-1105

2-Pyrazinecarboxylic acid

2,3,5-Trimethylpyrazine

Pyrazinamine

Product Information

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Ligustrazine (Standard) Related Classifications

HY-N0264R Related Classifications