Copy Link Print Information

Lorukafusp alfa

(Synonyms: APN-301; hu14.18-IL2; EMD 273063)
Kundenbewertung

Based on 1 Customer Validation

Lorukafusp alfa (14.18 mAb; hu14.18-IL2) is an immunocytokine consisting of the humanized 14.18 anti-GD2 mAb linked to IL210. Lorukafusp alfa has activity mediated by activation of antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity via the binding of hu14.18-IL2 to GD2 on the tumor cell surface, followed by binding to Fc receptors on effector cells along with activation of NK and T cells via IL2 receptor binding. Lorukafusp alfa has anti-tumor activity.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit: 97.8%
  • CAS. Nr.: 2131168-99-3
  • Molecular Weight:175.6 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Lorukafusp alfa
  • Experimental Validation Results for Lorukafusp alfa
  • Experimental Validation Results for Lorukafusp alfa
  • Lorukafusp alfa Chemical Structure
    Lorukafusp alfa Chemical Structure
CAS. Nr.: 2131168-99-3
Größe
Preis
Verfügbarkeit
Menge
Amount: USD 0.00
Please select quantity
or
or

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Lorukafusp alfa Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
  • Biologische Aktivität
  • Chemical Information
  • Reinheit & Dokumentation
  • Verweise
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products
Keywords
MOQ
Minimum order quantity
100 mg

Angebot einholen Auf Lager

Other size
Angebot einholen
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Einloggen
Registrieren
Sign in to MedChemExpress
Neuen Account Registrieren

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Human IL-2R-alpha/CD25 Protein (HEK293, C-His, HY-P70628) can bind Lorukafusp alfa. The EC50 for this effect is 5.85 ng/mL.

  • 1/16

    Immobilized Ganglioside GD2 (HY-165740) can bind Lorukafusp alfa. The EC50 for this effect is 365.7 ng/mL.

  • Lorukafusp alfa Chemical Structure
    1/16
  • Lorukafusp alfa
  • Immobilized Human IL-2R-alpha/CD25 Protein (HEK293, C-His, HY-P70628) can bind Lorukafusp alfa. The EC50 for this effect is 5.85 ng/mL.
  • Immobilized Ganglioside GD2 (HY-165740) can bind Lorukafusp alfa. The EC50 for this effect is 365.7 ng/mL.