country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-183552

Copy Link Print Information

mCPX

mCPX is a prodrug of the antifungal agent Ciclopirox olamine (CPX) (HY-B0450A). CPX exhibits bacteriostatic and iron-chelating activities, while mCPX enhances the iron stability of CPX. mCPX inherits the core mechanism pathway of CPX and can induce EBV lytic reactivation in EBV⁺ gastric cancer cells via the hypoxia pathway (HIF‑1α). mCPX is applicable to research related to EBV-positive gastric cancer.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 1351572-56-9
Formel: C₁₄H₁₉NO₃
Molecular Weight:249.31

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

mCPX Chemical Structure

CAS. Nr.: 1351572-56-9

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
- Parmacokinetics
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle HIF/HIF Prolyl-Hydroxylase Isoform-spezifische Produkte anzeigen :

In Vitro

mCPX induces EBV lytic cycle in SNU719 and AGSBX1 EBV⁺ gastric cancer cell lines with activity comparable to CPX, and has significantly greater resistance to iron-mediated inactivation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Parmacokinetics

Species	Dose	Route	T_1/2	T_max	C_max	AUC	AUC_0-∞	MRT	V_d	CL
Rat^[1]	14 mg/kg	i.p.	10.88 h	0.67 h	3085.04 μg/L	9195.38 μg/L·h	9455.28 μg/L·h	6.67 h	23.25 L/kg	1.48 L/h/kg
Rat^[1]	14 mg/kg	i.g.	5.01 h	1.50 h	511.88 μg/L	4332.53 μg/L·h	4350.86 μg/L·h	6.05 h	23.25 L/kg	3.22 L/h/kg

In Vivo

mCPX exhibits superior in vivo antitumor activity to CPX in the SNU719 xenograft mouse model^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 1351572-56-9
Molecular Weight 249.31
Formel C₁₄H₁₉NO₃
SMILES

O=C(C)ON(C(C1CCCCC1)=CC(C)=C2)C2=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Zhuang Y,et al. Targeting lytic cycle with ciclopirox derivative in Epstein-Barr Virus+ gastric cancer. Cancer Research. 2026 Apr 3;86(7_Supplement):213-.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen