Methsuximide (Standard)
Methsuximide (Standard) (Mesuximide (Standard); Celontin (Standard)) is the analytical standard of Methsuximide (HY-B1376). This product is intended for research and analytical applications. Methsuximide (Mesuximide) is an orally active succinimide-derived antiepileptic agent. Methsuximide interacts with cytochrome P-450, increases the level of hepatic microsomal cytochrome P-450, and inhibits or competes with the cytochrome P-450 CYP 2C9/10 subtype. Methsuximide can be used in epilepsy-related research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 77-41-8
- Formel: C12H13NO2
- Molecular Weight:203.24
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Product Information
Information
Anwendung
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 77-41-8
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Molecular Weight 203.24
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Formel C12H13NO2
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SMILES
O=C(C(C1=CC=CC=C1)(C)C2)N(C)C2=O
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Synonyms
Mesuximide (Standard); Celontin (Standard)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Orton TC, et al. Effect in rats of subacute administration of ethosuximide, methsuximide and phensuximide on hepatic microsomal enzymes and porphyrin turnover. Biochem Pharmacol. 1972 Aug 15;21(16):2253-61. [Content Brief]
[3]. Sigler M, et al. Effective and safe but forgotten: methsuximide in intractable epilepsies in childhood. Seizure. 2001 Mar;10(2):120-4. [Content Brief]
[4]. Besag FM, et al. Methsuximide lowers lamotrigine blood levels: A pharmacokinetic antiepileptic drug interaction. Epilepsia. 2000 May;41(5):624-7. [Content Brief]
[5]. Dobrinska MR, et al. Pharmacokinetics of methsuximide and a major metabolite in dogs. Journal of pharmaceutical sciences. 1977 May;66(5):688-92. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Methsuximide (Standard) Related Classifications
HY-B1376R Related Classifications
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Keywords
- Methsuximide (Standard)
- 77-41-8
- Mesuximide (Standard)
- Celontin (Standard)
- Reference Standards
- Cytochrome P450
- pentylenetetrazol-induced clonic seizures
- Sprague-Dawley rats
- CFHB Wistar rat liver microsomes
- Macaca rhesus monkeys
- cytochrome P-450
- chick embryo liver
- Webster strain mice
- electroshock-induced tonic extensor seizures
- CYP 2C9/10 isoform
- δ-aminolaevulinic acid synthetase
- Inhibitor
- inhibitor
- inhibit