mGluR2 modulator 2
mGluR2 modulator 2 (compound 2) is a potent, selective and orally bioavailable mGluR2 positive allosteric modulator with an EC50 value of 0.13 μM. mGluR2 modulator 2 can be used for researching antipsychotic.
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- CAS. Nr.: 1004614-86-1
- Formel: C20H22FN3
- Molecular Weight:323.41
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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mGluR2 0.13 μM (EC50) |
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Cell Line
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Type | Value | Description | References |
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| HEK293 | EC50 |
22 nM
Compound: 7b
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Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced intracellular calcium release by FLIPR assay
Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced intracellular calcium release by FLIPR assay
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[PMID: 21366332] |
Chemical Information
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CAS. Nr. 1004614-86-1
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Molecular Weight 323.41
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Formel C20H22FN3
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SMILES
CN1C2=CC=CC=C2N=C1CN3CCC(CC3)C4=CC=CC=C4F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
mGluR2 modulator 2 Related Classifications
HY-147528 Related Classifications
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