ONO-2570366
ONO-2570366 (Compound 11a) is an antagonist of the cysteinyl leukotriene receptors CysLT1R and CysLT2R (IC50 = 14 nM). ONO-2570366 inhibits the binding of LTD4asthma.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C30H30ClFN2O7
- Molecular Weight:585.02
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Alle Leukotriene Receptor Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
CysLT2 14 nM (IC50) |
CysLT1 |
Chemical Information
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Molecular Weight 585.02
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Formel C30H30ClFN2O7
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SMILES
O=C(O)[C@H]1OC2=C(C=CC=C2N(C1)CCCC(O)=O)NC(C3=CC=C(C=C3)OCCCCC4=CC(F)=CC=C4Cl)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
ONO-2570366 Related Classifications
HY-176921 Related Classifications
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