Ph-HTBA
Ph-HTBA is a high-affinity, brain-penetrating modulator for CaMKIIα. Ph-HTBA has binding affinity for CaMKIIα with a Kd value of 757 nM. Ph-HTBA can be used for the research of ischemia and neurodegenerative disorders.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2368927-41-5
- Formel: C19H18O3
- Molecular Weight:294.34
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
Kd: 757 nM (CaMKIIα)[1]
Ph-HTBA can inhibit HOCPCA binding with a Ki value of 1.4 μM[1].
Ph-HTBA has binding affinity for CaMKIIα with a Kd value of 757 nM[1].
Ph-HTBA (compound 1i) has a marked hub thermal stabilization effect along with a distinct CaMKIIα Trp403 flip upon binding[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2368927-41-5
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Molecular Weight 294.34
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Formel C19H18O3
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SMILES
O=C(O)/C=C1CCCC2=CC(C3=CC=CC=C3)=CC=C2C\1O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Ph-HTBA Related Classifications
HY-151797 Related Classifications
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