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Art. -Nr.: HY-125909

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Phenolic acid

Phenolic acid is an endogenous metabolite.

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CAS. Nr.: 29656-58-4
Formel: C₇H₈D₂O₃
Molecular Weight:144.16

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (237 KB)

Phenolic acid Chemical Structure

CAS. Nr.: 29656-58-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
- Clinical Trial
- Anwendung
Chemical Information
Reinheit & Dokumentation
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Phenolic acid is an endogenous metabolite.

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
Caco-2	IC₅₀	5 mM Compound: salicylic acid	Cytotoxicity against human Caco2 cells after 24 hrs by MTT assay Cytotoxicity against human Caco2 cells after 24 hrs by MTT assay	[PMID: 26617961]
DU-145	IC₅₀	>100 μM Compound: 2; Salic	Antiproliferative activity against human DU-145 cells incubated for 48 hrs by MTT assay Antiproliferative activity against human DU-145 cells incubated for 48 hrs by MTT assay	[PMID: 36257283]
HEK293	IC₅₀	>15 mM Compound: Salicylate	Cytotoxicity against HEK293 cells harboring pendrin P123S mutant after 72 hrs by MTT assay Cytotoxicity against HEK293 cells harboring pendrin P123S mutant after 72 hrs by MTT assay	[PMID: 28341401]
HT-29	IC₅₀	>100 μM Compound: 2; Salic	Antiproliferative activity against human HT-29 cells incubated for 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells incubated for 48 hrs by MTT assay	[PMID: 36257283]
MCF7	IC₅₀	>100 μM Compound: 2; Salic	Antiproliferative activity against human MCF7 cells incubated for 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells incubated for 48 hrs by MTT assay	[PMID: 36257283]
RAW264.7	CC₅₀	>40 μM Compound: 1	Cytotoxicity against mouse RAW264.7 cells assessed as reduction in survival rate after 24 hrs by MTT assay Cytotoxicity against mouse RAW264.7 cells assessed as reduction in survival rate after 24 hrs by MTT assay	[PMID: 25200306]
Sf9	IC₅₀	500 μM Compound: salicylic acid	Inhibition of human recombinant COX1 expressed in Sf9 cell microsomes assessed as reduction in conversion of arachidonic acid to PGE2 incubated for 5 mins by HTRF assay Inhibition of human recombinant COX1 expressed in Sf9 cell microsomes assessed as reduction in conversion of arachidonic acid to PGE2 incubated for 5 mins by HTRF assay	[PMID: 27046190]

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Anwendung

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS. Nr. 29656-58-4
Molecular Weight 144.16
Formel C₇H₈D₂O₃
SMILES

OC([2H])=O.[D1]O[H].C1=CC=CC=C1
Structure Classification
- Others
Initial Source
- Endogenous metabolite
- Human Gut Microbiota Metabolites
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.