Phenopyrazone
Phenopyrazone (Diphenox), a derivative of Antipyrine (HY-B0171), exhibits oral activity as well as analgesic, antipyretic, anti-inflammatory, and antidiarrheal properties. Phenopyrazone can be used in research related to headache, rheumatism, chronic diarrhea and varicose veins.
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- CAS. Nr.: 3426-01-5
- Formel: C15H12N2O2
- Molecular Weight:252.27
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vivo
Phenopyrazone (p.o.; single dose) alone has no detectable antipyretic activity against yeast-induced fever in rats at oral doses up to 640 mg/kg[1].
Phenopyrazone (p.o.) exhibits anti-inflammatory activity against carrageenin-induced hind paw edema in rats with an ED50 of 574.0 mg/kg p.o[1].
Phenopyrazone (oral administration) serves as a component in preparations for venous disorders and induces pseudo‑lupus syndrome accompanied by high‑titer antimitochondrial antibodies[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 3426-01-5
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Molecular Weight 252.27
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Formel C15H12N2O2
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SMILES
O=C1NN(C=2C=CC=CC2)C(=O)C1C=3C=CC=CC3
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Synonyms
Diphenox; Kr 132
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Phenopyrazone Related Classifications
HY-105592 Related Classifications
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