PKZ18
PKZ18 is an antibiotic and inhibits bacterial growth, with MIC values of 32-64 μg/mL against most Gram-positive bacteria. PKZ18 inhibits in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria and directly reduces T-box transcriptional read-through of the associated genes. PKZ18 prevents the codon-anticodon reading required for tRNA binding and is refractory to resistance.
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- CAS. Nr.: 849658-87-3
- Formel: C22H26N2O3S
- Molecular Weight:398.52
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 849658-87-3
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Molecular Weight 398.52
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Formel C22H26N2O3S
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SMILES
CC(S1)=C(C2=CC=C(C=C2)C(C)C)N=C1NC([C@@H]3[C@@H]([C@]4([H])C[C@@]3([H])CC4)C(O)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PKZ18 Related Classifications
HY-169810 Related Classifications
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