Pomalidomide-C2-acid
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Pomalidomide-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
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- Reinheit: 99.78%
- CAS. Nr.: 2225940-46-3
- Formel: C16H15N3O6
- Molecular Weight:345.31
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Alle E3 Ligase Ligand-Linker Conjugates Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
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Cereblon |
Chemical Information
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CAS. Nr. 2225940-46-3
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Appearance Solid
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Molecular Weight 345.31
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Formel C16H15N3O6
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Color Light yellow to yellow
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SMILES
O=C(CCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 50 mg/mL (144.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (272 KB)
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8959 mL | 14.4797 mL | 28.9595 mL | 72.3987 mL |
| 5 mM | 0.5792 mL | 2.8959 mL | 5.7919 mL | 14.4797 mL | |
| 10 mM | 0.2896 mL | 1.4480 mL | 2.8959 mL | 7.2399 mL | |
| 15 mM | 0.1931 mL | 0.9653 mL | 1.9306 mL | 4.8266 mL | |
| 20 mM | 0.1448 mL | 0.7240 mL | 1.4480 mL | 3.6199 mL | |
| 25 mM | 0.1158 mL | 0.5792 mL | 1.1584 mL | 2.8959 mL | |
| 30 mM | 0.0965 mL | 0.4827 mL | 0.9653 mL | 2.4133 mL | |
| 40 mM | 0.0724 mL | 0.3620 mL | 0.7240 mL | 1.8100 mL | |
| 50 mM | 0.0579 mL | 0.2896 mL | 0.5792 mL | 1.4480 mL | |
| 60 mM | 0.0483 mL | 0.2413 mL | 0.4827 mL | 1.2066 mL | |
| 80 mM | 0.0362 mL | 0.1810 mL | 0.3620 mL | 0.9050 mL | |
| 100 mM | 0.0290 mL | 0.1448 mL | 0.2896 mL | 0.7240 mL |
Pomalidomide-C2-acid Related Classifications
HY-150006 Related Classifications
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