Protizinic acid
Protizinic acid is an orally active non-steroidal antiinflammatory agent with antiinflammatory and antipyretic activity. Protizinic acid inhibits phospholipase A2 (PLA2) activity, and the IC50 value is 210 μM.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 13799-03-6
- Formel: C17H17NO3S
- Molecular Weight:315.39
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Alle Phospholipase Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
Beschreibung
IC50 & Target
[2]|
PLA2 210 μM (IC50) |
In Vitro
Protizinic acid not only inhibits the in vitro generation of leukokinin but also antagonizes to it on the receptor site of leukokinin[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Oral administration of 30 mg/kg of Protizinic acid significantly inhibits arachidonic acid-induced erythema in guinea pigs[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS. Nr. 13799-03-6
-
Molecular Weight 315.39
-
Formel C17H17NO3S
-
SMILES
CN1C2=C(C=CC(C(C)C(O)=O)=C2)SC3=CC(OC)=CC=C13
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. K Suzuki, et al. Effects of protizinic acid on leukokinin generation and its physiological action. Agents Actions. 1984 Jun;14(5-6):699-706. [Content Brief]
[2]. H Ohnishi, et al. Effects of protizinic acid on the prostaglandins system and the production of oxygen radicals. Nihon Yakurigaku Zasshi. 1982 Jun;79(6):561-9. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)