45 Results for "

TRAIL-R

" in MedChemExpress (MCE) Product Catalog:
Products (45)

45 Results for "TRAIL-R" in MCE Product Catalog:

1
1 Cited Publications
Art. -Nr.: HY-P99934
CAS. Nr.: 1820660-69-2
Synonyms: ABBV-621

Forschungsgebiete:  

Cancer

Eftozanermin alfa (ABBV-621) is a tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa is a fusion protein consisting of a mutant immunoglobulin G1-Fc linked to 2 single-chain trimers of TRAIL. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors (DR4 receptor and DR5 receptor) with Kds of 780 nM and 635 nM. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies .
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Art. -Nr.: HY-P99260
CAS. Nr.: 896731-82-1
Synonyms: AMG 655; TRAIL-R2 mAb; Human Anti-TNFRSF10B Recombinant Antibody

Target:  

TNF Receptor

Forschungsgebiete:  

Cancer

Conatumumab (AMG 655) is a human monoclonal agonist antibody against human death receptor 5 (DR5, TRAILR2) (Kd: 1 nM for the long form of DR5, 0.8 nM for the short form of DR5). Conatumumab induces apoptosis via caspase activation. Conatumumab can be used in the research of cancers. .
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Art. -Nr.: HY-148875
CAS. Nr.: 2247398-68-9
Reinheit:  99.78%
Forschungsgebiete:  

Cancer

Py-MAA-Val-Cit-PAB-MMAE is a drug-Linker conjugates for ADC, which is composed of MMAE (HY-15162) and Py-MAA-Val-Cit-PAB linked. Py-MAA-Val-Cit-PAB-MMAE can be used to synthesize Zapadcine-3a, which targeting TRAILR2. Zapadcine-3a has broad-spectrum anti-tumor activity, and can specifically kill TRAILR2-positive tumors .
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Art. -Nr.: HY-P99299
CAS. Nr.: 845816-02-6
Synonyms: HGS-ETR 2; ETR2-ST01

Target:  

Apoptosis

Forschungsgebiete:  

Cancer

Lexatumumab (HGS-ETR 2) is a human agonistic TRAIL receptor 2 (TRAIL-R2, DR5, APO-2) IgG4κ type monoclonal antibody. Lexatumumab induces apoptosis in malignant mesothelioma. Lexatumumab can be used for malignant pleural mesothelioma (MPM) research .
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Art. -Nr.: HY-P99270
CAS. Nr.: 918127-53-4
Synonyms: CS-1008; Anti-Human TRAIL-R2 Recombinant Antibody

Target:  

Apoptosis

Forschungsgebiete:  

Cancer

Tigatuzumab (CS-1008) is a humanized IgG1 monoclonal antibody targets death receptor 5 (DR5). Tigatuzumab induces cell apoptosis of cancer cells and inhibits tumor growth in vivo. Tigatuzumab can be used for the research of cancer .
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Art. -Nr.: HY-P99265
CAS. Nr.: 658052-09-6
Synonyms: HGS-ETR1; Anti-Human TNFRSF10A Recombinant Antibody

Target:  

Inhibitory Antibodies

Forschungsgebiete:  

Cancer

Mapatumumab (HGS-ETR1) is a fully human IgG1 agonistic monoclonal antibody that targets tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1). Mapatumumab can be used for the research of cancer .
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Art. -Nr.: HY-P78529
Reinheit:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFRSF10A; Death Receptor 4; TNF Receptor Superfamily Member 10a; TRAIL Receptor 1; TRAILR1; TRAIL-R1; DR4; Tumor Necrosis Factor Receptor Superfamily Member 10a Variant 2; TRAILR-1; Tumor Necrosis Factor Receptor Superfamily Member 10a; CD261; Alternativ
Species:  
Human
Source:  
HEK293
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Art. -Nr.: HY-P78219
Reinheit:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFRSF10A; Death Receptor 4; TNF Receptor Superfamily Member 10a; TRAIL Receptor 1; TRAILR1; TRAIL-R1; DR4; Tumor Necrosis Factor Receptor Superfamily Member 10a Variant 2; TRAILR-1; Tumor Necrosis Factor Receptor Superfamily Member 10a; CD261; Alternativ
Species:  
Human
Source:  
HEK293
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Art. -Nr.: HY-P72440
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF10A; Death Receptor 4; TNF Receptor Superfamily Member 10a; TRAIL Receptor 1; TRAILR1; TRAIL-R1; DR4; Tumor Necrosis Factor Receptor Superfamily Member 10a Variant 2; TRAILR-1; Tumor Necrosis Factor Receptor Superfamily Member 10a; CD261; Alternativ
Species:  
Human
Source:  
HEK293
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Art. -Nr.: HY-P74500
Reinheit:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF10A; Death Receptor 4; TNF Receptor Superfamily Member 10a; TRAIL Receptor 1; TRAILR1; TRAIL-R1; DR4; Tumor Necrosis Factor Receptor Superfamily Member 10a Variant 2; TRAILR-1; Tumor Necrosis Factor Receptor Superfamily Member 10a; CD261; Alternativ
Species:  
Human
Source:  
HEK293
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Art. -Nr.: HY-P74501
Reinheit:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF10A; Death Receptor 4; TNF Receptor Superfamily Member 10a; TRAIL Receptor 1; TRAILR1; TRAIL-R1; DR4; Tumor Necrosis Factor Receptor Superfamily Member 10a Variant 2; TRAILR-1; Tumor Necrosis Factor Receptor Superfamily Member 10a; CD261; Alternativ
Species:  
Human
Source:  
HEK293
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Art. -Nr.: HY-P76863
Reinheit:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF10D; TNF-Related Apoptosis-Inducing Ligand Receptor 4; TNF Receptor Superfamily Member 10d; TRAIL Receptor With A Truncated Death Domain; TRAILR4; TRAIL Receptor 4; TRUNDD; Decoy Receptor 2; DcR2; TRAIL-R4; CD264; TNF Receptor-Related Receptor For T
Species:  
Human
Source:  
HEK293
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Art. -Nr.: HY-P76865
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF10D; TNF-Related Apoptosis-Inducing Ligand Receptor 4; TNF Receptor Superfamily Member 10d; TRAIL Receptor With A Truncated Death Domain; TRAILR4; TRAIL Receptor 4; TRUNDD; Decoy Receptor 2; DcR2; TRAIL-R4; CD264; TNF Receptor-Related Receptor For T
Species:  
Rhesus Macaque
Source:  
HEK293
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Art. -Nr.: HY-P78221
Reinheit:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFRSF10D; TNF-Related Apoptosis-Inducing Ligand Receptor 4; TNF Receptor Superfamily Member 10d; TRAIL Receptor With A Truncated Death Domain; TRAILR4; TRAIL Receptor 4; TRUNDD; Decoy Receptor 2; DcR2; TRAIL-R4; CD264; TNF Receptor-Related Receptor For T
Species:  
Human
Source:  
HEK293
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Art. -Nr.: HY-P72439
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF10D; TNF-Related Apoptosis-Inducing Ligand Receptor 4; TNF Receptor Superfamily Member 10d; TRAIL Receptor With A Truncated Death Domain; TRAILR4; TRAIL Receptor 4; TRUNDD; Decoy Receptor 2; DcR2; TRAIL-R4; CD264; TNF Receptor-Related Receptor For T
Species:  
Human
Source:  
HEK293
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Art. -Nr.: HY-P76864
Reinheit:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF10D; TNF-Related Apoptosis-Inducing Ligand Receptor 4; TNF Receptor Superfamily Member 10d; TRAIL Receptor With A Truncated Death Domain; TRAILR4; TRAIL Receptor 4; TRUNDD; Decoy Receptor 2; DcR2; TRAIL-R4; CD264; TNF Receptor-Related Receptor For T
Species:  
Rhesus Macaque
Source:  
HEK293
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Art. -Nr.: HY-P78531
Reinheit:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFRSF10D; TNF-Related Apoptosis-Inducing Ligand Receptor 4; TNF Receptor Superfamily Member 10d; TRAIL Receptor With A Truncated Death Domain; TRAILR4; TRAIL Receptor 4; TRUNDD; Decoy Receptor 2; DcR2; TRAIL-R4; CD264; TNF Receptor-Related Receptor For T
Species:  
Human
Source:  
HEK293
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Art. -Nr.: HY-P87404
Synonyms: CD261; APO2; DR4; TRAILR1; TNFRSF10A; Tumor necrosis factor receptor superfamily member 10A; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1

Host:  

Rabbit

Application:  

WB, ICC/IF, FC

Reactivity:  

Human

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Art. -Nr.: HY-P87404A
Synonyms: CD261; APO2; DR4; TRAILR1; TNFRSF10A; Tumor necrosis factor receptor superfamily member 10A; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1

Host:  

Rabbit

Application:  

WB, ICC/IF, FC

Reactivity:  

Human

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Art. -Nr.: HY-P70815
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF10C; Decoy TRAIL Receptor Without Death Domain; TNF Receptor Superfamily Member 10c; Lymphocyte Inhibitor Of TRAIL; TRAILR3; Decoy Receptor 1; DcR1; TRAIL-R3; TRID; TRAIL Receptor Without An Intracellular Domain; LIT; Cytotoxic TRAIL Receptor-3; CD2
Species:  
Human
Source:  
HEK293
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