41 Results for "

TRAIL-R

" in MedChemExpress (MCE) Product Catalog:
Products (41)

41 Results for "TRAIL-R" in MCE Product Catalog:

1
1 Cited Publications
Art. -Nr.: HY-P99934
CAS. Nr.: 1820660-69-2
Synonyms: ABBV-621

Forschungsgebiete:  

Cancer

Eftozanermin alfa (ABBV-621) is a tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa is a fusion protein consisting of a mutant immunoglobulin G1-Fc linked to 2 single-chain trimers of TRAIL. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors (DR4 receptor and DR5 receptor) with Kds of 780 nM and 635 nM. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies .
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Art. -Nr.: HY-P99260
CAS. Nr.: 896731-82-1
Synonyms: AMG 655; TRAIL-R2 mAb; Human Anti-TNFRSF10B Recombinant Antibody

Target:  

TNF Receptor

Forschungsgebiete:  

Cancer

Conatumumab (AMG 655) is a human monoclonal agonist antibody against human death receptor 5 (DR5, TRAILR2) (Kd: 1 nM for the long form of DR5, 0.8 nM for the short form of DR5). Conatumumab induces apoptosis via caspase activation. Conatumumab can be used in the research of cancers. .
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Art. -Nr.: HY-148875
CAS. Nr.: 2247398-68-9
Reinheit:  99.78%
Forschungsgebiete:  

Cancer

Py-MAA-Val-Cit-PAB-MMAE is a drug-Linker conjugates for ADC, which is composed of MMAE (HY-15162) and Py-MAA-Val-Cit-PAB linked. Py-MAA-Val-Cit-PAB-MMAE can be used to synthesize Zapadcine-3a, which targeting TRAILR2. Zapadcine-3a has broad-spectrum anti-tumor activity, and can specifically kill TRAILR2-positive tumors .
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Art. -Nr.: HY-P99299
CAS. Nr.: 845816-02-6
Synonyms: HGS-ETR 2; ETR2-ST01

Target:  

Apoptosis

Forschungsgebiete:  

Cancer

Lexatumumab (HGS-ETR 2) is a human agonistic TRAIL receptor 2 (TRAIL-R2, DR5, APO-2) IgG4κ type monoclonal antibody. Lexatumumab induces apoptosis in malignant mesothelioma. Lexatumumab can be used for malignant pleural mesothelioma (MPM) research .
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Art. -Nr.: HY-P99270
CAS. Nr.: 918127-53-4
Synonyms: CS-1008; Anti-Human TRAIL-R2 Recombinant Antibody

Target:  

Apoptosis

Forschungsgebiete:  

Cancer

Tigatuzumab (CS-1008) is a humanized IgG1 monoclonal antibody targets death receptor 5 (DR5). Tigatuzumab induces cell apoptosis of cancer cells and inhibits tumor growth in vivo. Tigatuzumab can be used for the research of cancer .
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Art. -Nr.: HY-P99265
CAS. Nr.: 658052-09-6
Synonyms: HGS-ETR1; Anti-Human TNFRSF10A Recombinant Antibody

Target:  

Inhibitory Antibodies

Forschungsgebiete:  

Cancer

Mapatumumab (HGS-ETR1) is a fully human IgG1 agonistic monoclonal antibody that targets tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1). Mapatumumab can be used for the research of cancer .
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Art. -Nr.: HY-P78529
Reinheit:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: DR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365
Species:  
Source:  
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Art. -Nr.: HY-P78219
Reinheit:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: DR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365
Species:  
Source:  
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Art. -Nr.: HY-P84855
Synonyms: DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Monkey

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Art. -Nr.: HY-P84856
Synonyms: DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Mouse

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Art. -Nr.: HY-P84855A
Synonyms: DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Monkey

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Art. -Nr.: HY-P84856A
Synonyms: DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Mouse

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Art. -Nr.: HY-P78567
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF10B; TRAILR2; TRAIL-R2; CD262; DR5; KILLER; TRICK2; ZTNFR9; TRICKB
Species:  
Source:  
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Art. -Nr.: HY-P74497
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10B; CD262; TRAIL-R2; DR5; KILLER; TRAILR2; ZTNFR9
Species:  
Source:  
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Art. -Nr.: HY-P74498
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10B; CD262; TRAIL-R2; DR5; KILLER; TRAILR2; ZTNFR9
Species:  
Source:  
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Art. -Nr.: HY-P72779
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10B; Death receptor 5; TRAIL-R2; CD262; TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9
Species:  
Source:  
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Art. -Nr.: HY-P76863
Reinheit:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10D; DcR2; TRAIL-R4; CD264; TRUNDD
Species:  
Source:  
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Art. -Nr.: HY-P72439
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10D; DcR2; TRAIL receptor 4; TRAIL-R4; CD264; TNFRSF10D; DCR2; TRAILR4; TRUNDD
Species:  
Source:  
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Art. -Nr.: HY-P76865
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10D; DcR2; TRAIL-R4; CD264; TRUNDD
Species:  
Source:  
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Art. -Nr.: HY-P76864
Reinheit:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10D; DcR2; TRAIL-R4; CD264; TRUNDD
Species:  
Source:  
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